Urinary growth hormone measurements as a marker of renal tubular function in diabetes mellitus

Turner, G. A.; Coates, Philip A.; Porter, Sam; Peters, John R.; Woodhead, J. S.

doi:10.1016/0009-8981(93)90003-m

Cited by 7 publications

(1 citation statement)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Hourd and Edwards (17) demonstrated that the renal clearance of GH was signi cantly greater in diabetic than in normal children. Turner et al (32) showed that urinary GH excretion was reduced with improved glycaemic control, whereas others have not been able to relate glycaemic control to the amount of GH excreted in urine (18). The lack of reduction in urinary GH excretion in this investigation could thus be related to the complex mechanisms by which GH is excreted into urine, particularly in diabetic patients, and does not necessarily exclude effects of PZP treatment on pituitary GH secretion and/or secretory pattern.…”

Section: Discussionmentioning

confidence: 58%

Anticholinergic treatment improves glycaemic control in adolescent girls with insulin-dependent diabetes mellitus

Halldin¹,

Åman²,

Brismar³

et al. 2001

Acta Paediatrica

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 58%

Anticholinergic treatment improves glycaemic control in adolescent girls with insulin-dependent diabetes mellitus

Halldin¹,

Åman²,

Brismar³

et al. 2001

Acta Paediatrica

View full text Add to dashboard Cite

show abstract

Detection of human growth hormone doping in urine: out of competition tests are necessary

Saugy

Cardis

Schweizer

et al. 1996

Journal of Chromatography B: Biomedical Sciences and Applicatio

View full text Add to dashboard Cite

The Promise of Systems Biology for Diabetic Kidney Disease

Brosius

2018

Advances in Chronic Kidney Disease

View full text Add to dashboard Cite

Diabetic kidney disease (DKD) has a complex and prolonged pathogenesis involving many cell types in the kidney as well as extrarenal factors. It is clinically silent for many years after the onset of diabetes and usually progresses over decades. Given this complexity, a comprehensive and unbiased molecular approach is best suited to help identify the most critical mechanisms responsible for progression of DKD and those most suited for targeted intervention. Systems biological investigations provide such an approach since they examine the entire network of molecular changes that occur in a disease process in a comprehensive way instead of focusing on a single abnormal molecule or pathway. Systems biological studies can also start with analysis of the disease in humans, not in animal or cell culture models that often poorly reproduce the changes in human DKD. Indeed, in the last decade, systems biological approaches have led to the identification of critical molecular abnormalities in DKD and have directly led to development of new biomarkers and potential treatments for DKD.

show abstract

Urinary growth hormone measurements as a marker of renal tubular function in diabetes mellitus

Cited by 7 publications

References 32 publications

Anticholinergic treatment improves glycaemic control in adolescent girls with insulin-dependent diabetes mellitus

Anticholinergic treatment improves glycaemic control in adolescent girls with insulin-dependent diabetes mellitus

Detection of human growth hormone doping in urine: out of competition tests are necessary

The Promise of Systems Biology for Diabetic Kidney Disease

Contact Info

Product

Resources

About