1957
DOI: 10.1097/00000658-195704000-00004
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Urinary Output of Adrenaline and Noradrenaline in Sevre Thermal Burns

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Cited by 167 publications
(56 citation statements)
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“…5,7,55,56 In the present study, we found that a severe burn injury increases serum and urine cortisol. Urine cortisol increased 5-8-fold and remained elevated throughout the entire acute hospital stay.…”
Section: Discussionsupporting
confidence: 62%
“…5,7,55,56 In the present study, we found that a severe burn injury increases serum and urine cortisol. Urine cortisol increased 5-8-fold and remained elevated throughout the entire acute hospital stay.…”
Section: Discussionsupporting
confidence: 62%
“…As a primordial response to stressful events such as critical injury, marked increases in endogenous release of catecholamines have been documented in patients resulting in a ten-fold increase in circulating levels (Angus and Wax, 2001;Benedict and Grahame-Smith, 1978;Frayn, 1986;Goodall et al, 1957;Wilmore and Aulick, 1978). Furthermore, critically injured patients are often administered exogenous catecholamines to maintain cardiovascular homeostasis.…”
Section: Discussionmentioning
confidence: 99%
“…line per 24 hours (7,22). It is further known that the adrenal gland normally synthesizes adrenaline with such rapidity (23)(24)(25) that only under unusual circumstances can the adrenal medulla be depleted of its adrenaline supply (1,3).…”
mentioning
confidence: 99%
“…It is further known that the adrenal gland normally synthesizes adrenaline with such rapidity (23)(24)(25) that only under unusual circumstances can the adrenal medulla be depleted of its adrenaline supply (1,3). It has been shown that most patients who survive severe thermal burns excrete daily large amounts of adrenaline and noradrenaline, and that this elevated rate of excretion continues for weeks without any recognizable failure in the adrenal gland's ability to produce adrenaline (7). However, of the burned patients who died, approximately two-thirds showed a markedly depressed adrenaline output at the time of death.…”
mentioning
confidence: 99%
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