2012
DOI: 10.1016/j.toxlet.2011.11.033
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Urinary phthalate monoesters concentration in couples with infertility problems

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Cited by 86 publications
(39 citation statements)
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“…In recent years, several studies have demonstrated a relationship between infertility and DEHP [29,30]. The harmful contribution of DEHP to infertility, especially to female reproduction, has been hard to ignore.…”
Section: Discussionmentioning
confidence: 99%
“…In recent years, several studies have demonstrated a relationship between infertility and DEHP [29,30]. The harmful contribution of DEHP to infertility, especially to female reproduction, has been hard to ignore.…”
Section: Discussionmentioning
confidence: 99%
“…In a small case control study comprising 56 couples with and 56 without infertility, infertile partners excreted higher concentrations of five phthalate metabolites in comparison to fertile partners (22). A cohort study comprising couples planning pregnancy and prospectively followed for six cycles reported that mEHP but not five other phthalates was significantly associated with approximately a three-fold increased odds of pregnancy loss (23).…”
Section: Introductionmentioning
confidence: 97%
“…In Generation R, a large pregnancy cohort study conducted in the Netherlands, occupational exposure to phthalates was assessed using a job-exposure matrix, and was reported to be suggestive of longer TTP (22,23). In Italy, concentrations of several phthalate metabolites were assessed in 56 infertile couples from an ART center, and they were found to be significantly higher than in the control group of fertile couples (24). Recently, in the LIFE Study, no phthalate metabolite in female urine was statistically associated with a longer TTP, although one metabolite [mono (3-carboxypropyl) phthalate] was associated with a shorter TTP.…”
mentioning
confidence: 99%