Urinary stone composition analysis and clinical characterization of 1520 patients in central China

Abstract

A total of 1520 patients with urinary stones from central China were collected and analysed by Fourier transform infrared spectroscopy between October 1, 2016 and December 31, 2019. For all patients, age, sex, comorbidities, stone location, laboratory examination and geographic region were collected. The most common stone component was calcium oxalate (77.5%), followed by calcium phosphate (8.7%), infection stone (7.6%), uric acid (UA) stone (5.3%)and cystine (0.9%). The males had more calcium oxalate stones (p < 0.001), while infection stone and cystine stones occurred more frequently in females (p < 0.001). The prevalence peak occurred at 41–60 years in both men and women. UA stones occurred frequently in patients with lower urinary pH (p < 0.001), while neutral urine or alkaline urine (p < 0.001) and urinary infection (p < 0.001) were more likely to be associated with infection stone stones. Patients with high levels of serum creatinine were more likely to develop UA stones (p < 0.001). The proportion of UA stones in diabetics was higher (p < 0.001), and the incidence of hypertension was higher in patients with UA stones (p < 0.001). Compared to the other types, more calcium oxalate stones were detected in the kidneys and ureters (p < 0.001), whereas struvite stones were more frequently observed in the lower urinary tract (p = 0.001). There was no significant difference in stone composition across the Qinling-Huaihe line in central China except UA stones, which were more frequently observed in patients south of the line (p < 0.001).

Clinical Characteristics of Bacterial Spectrum and Antimicrobial Resistance in Urine and Stone Cultures From Patients With Kidney Stone Disease

“…In this study, the proportion of calcium oxalate stones (55.2%) was much lower than that reported in Zhang's article (77.5%) [15], and the patients with uric acid stones were signi cantly more common. The explanation might be different dietary habits.…”

Triglyceride–Glucose Index as a Novel Biomarker in the Occurrence of Kidney Stones: A Cross-Sectional Population-Based Study

“…It was supposed that uric acid excretion functions as the mechanism that may illustrate the stone formation. 16 All the results supported that IR was the risk factor for kidney stones and would contribute to the occurrence prediction.…”

Preputial Stones as a Rare Complication of Buried Penis: A Case Report

“…Carbonate, ammonia, magnesium, and phosphate were detected in the stones extracted from our patient. Thus, we de-duced that the stones were calcium phosphate stones and magnesium ammonium phosphate stones [8]. Calcium phosphate stones are the second most common stones found in the urinary tract and are most likely caused by the accumulation of urine inside the prepuce.…”