Urinary tract infection caused by Mycobacterium terrae complex

Chan, TM; Ng, Ktp; Ho, A.; Scheel, Olaf; Lai, Ching‐Long; Leung, R. C. K.

doi:10.1016/s0962-8479(96)90055-6

Cited by 10 publications

(6 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…M. simiae has been isolated from two Ugandan HIV infected patients [41]. The other NTM detected in this study have been isolated from patients in different parts of the world, and may cause clinical syndromes: chronic bronchopulmonary disease, lymphadenitis, skin and soft tissue disease, skeletal disease, and disseminated and catheter-related infections [39,40,42-46]. In humans, immunocompromised individuals such as the malnourished, HIV/AIDS infected, children or the elderly are often affected [47].…”

Section: Discussionmentioning

confidence: 99%

“…Bacteria in the M. terrae complex and M. hiberniae have been documented to be resistant to multiple anti-tuberculosis drugs [46]. M. nonchromogenicum and M. terrae , found to be non pathogenic for guinea pigs, pigs and rabbits are known to provoke a non specific hypersensitivity reaction to bovine tuberculin in guinea pigs, pigs and cattle [16].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Isolation of non-tuberculous mycobacteria from pastoral ecosystems of Uganda: Public Health significance

et al. 2011

View full text Add to dashboard Cite

BackgroundThe importance of non-tuberculous mycobacteria (NTM) infections in humans and animals in sub-Saharan Africa at the human-environment-livestock-wildlife interface has recently received increased attention. NTM are environmental opportunistic pathogens of humans and animals. Recent studies in pastoral ecosystems of Uganda detected NTM in humans with cervical lymphadenitis and cattle with lesions compatible with bovine tuberculosis. However, little is known about the source of these mycobacteria in Uganda. The aim of this study was to isolate and identify NTM in the environment of pastoral communities in Uganda, as well as assess the potential risk factors and the public health significance of NTM in these ecosystems.MethodA total of 310 samples (soil, water and faecal from cattle and pigs) were examined for mycobacteria. Isolates were identified by the INNO-Lipa test and by 16S rDNA sequencing. Additionally, a questionnaire survey involving 231 pastoralists was conducted during sample collection. Data were analysed using descriptive statistics followed by a multivariable logistic regression analysis.ResultsForty-eight isolates of NTM were detected; 25.3% of soil samples, 11.8% of water and 9.1% from animal faecal samples contained mycobacteria. Soils around water sources were the most contaminated with NTM (29.8%). Of these samples, M. fortuitum-peregrinum complex, M. avium complex, M. gordonae, and M. nonchromogenicum were the most frequently detected mycobacteria. Drinking untreated compared to treated water (OR = 33), use of valley dam versus stream water for drinking and other domestic use (OR = 20), sharing of water sources with wild primates compared to antelopes (OR = 4.6), sharing of water sources with domestic animals (OR = 5.3), and close contact with cattle or other domestic animals (OR = 13.8) were the most plausible risk factors for humans to come in contact with NTM in the environment.ConclusionsThe study detected a wide range of potentially pathogenic NTM from the environment around the pastoral communities in Uganda. Drinking untreated water and living in close contact with cattle or other domestic animals may be risk factors associated with the possibility of humans and animals acquiring NTM infections from these ecosystems.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Isolation of non-tuberculous mycobacteria from pastoral ecosystems of Uganda: Public Health significance

et al. 2011

View full text Add to dashboard Cite

show abstract

“…Therefore, cultures positive for these agents should be carefully interpreted. To date, few cases of human disease caused by M. terrae complex have been reported [3,4,[5][6][7][8][9][10][11][12][13][14][15][16], and isolation of M. terrae complex from HIV-infected patients has been described only in 1 series of 35 patients (isolation occurred only in 1 case, apparently without clinical disease) [1]. Our patient, therefore, represents the first HIV-related case of clinically relevant disseminated infection by M. terrae.…”

Section: Disseminated Mycobacterium Terrae Infection In a Patient Witmentioning

confidence: 90%

“…Up to 18% of isolates of nontuberculous mycobacteria [1,2] that are recovered from humans are M. terrae complex organisms, and these isolates are rarely related to clinical manifestations, thus signifying nonpathogenic colonization. A few cases of human disease that involved joints [3,4], lungs [5][6][7][8][9][10], skin [11], gut [12], urinary tract [13], and lymph nodes [14], or appeared as disseminated disease have been described elsewhere [15,16] lation occurred only in 1 case) [1], but clinical manifestations were not mentioned. We describe here an HIV-infected patient with disseminated infection by M. terrae that was associated with progressive pulmonary and cutaneous disease.…”

Section: Disseminated Mycobacterium Terrae Infection In a Patient Witmentioning

confidence: 99%

Disseminated Mycobacterium terrae Infection in a Patient with Advanced Human Immunodeficiency Virus Disease

Carbonara

Tortoli

Costa

et al. 2000

Clinical Infectious Diseases

View full text Add to dashboard Cite

Mycobacterium terrae has been rarely implicated in human disease and never in patients infected with human immunodeficiency virus (HIV). We describe an HIV-infected patient with disseminated infection by M. terrae with pulmonary and cutaneous clinical manifestations. M. terrae was isolated from both sputum and urine, and identified by both conventional tests and high-performance liquid chromatography. Clinical and microbiological characteristics of this case are compared with those reported in the literature.

show abstract

“…Congenital anomalies of the urogenital tract, renal cysts, kidney transplantation and urolithiasis significantly increase the risk of developing UGTB. The incidence of TB has been estimated to be as much as 10-fold higher among renal failure patients than among the general population [Chan et al 1996;Gusmão et al 1998;Kulchavenya and Muzyko, 2007;Korzeniewska et al 2009;Rabbani et al 2011;Takeshita et al 2012].…”

Section: Predispositionmentioning

confidence: 99%

Best practice in the diagnosis and management of urogenital tuberculosis

Kulchavenya

2013

Therapeutic Advances in Urology

View full text Add to dashboard Cite

Tuberculosis (TB) is a current public health problem, remaining the most common worldwide cause of mortality from infectious diseases. Urogenital tuberculosis (UGTB) is the second most common form of extrapulmonary TB in countries with severe epidemic situations and the third most common form in regions with a low incidence of TB. In this article we present the terminology, epidemiology and classification of UGTB, as well as describing the laboratory findings and clinical features and approaches to chemotherapy as well as surgery.

show abstract

Urinary tract infection caused by Mycobacterium terrae complex

Cited by 10 publications

References 6 publications

Isolation of non-tuberculous mycobacteria from pastoral ecosystems of Uganda: Public Health significance

Isolation of non-tuberculous mycobacteria from pastoral ecosystems of Uganda: Public Health significance

Disseminated Mycobacterium terrae Infection in a Patient with Advanced Human Immunodeficiency Virus Disease

Best practice in the diagnosis and management of urogenital tuberculosis

Contact Info

Product

Resources

About