Urinary tract infection in very low birth weight preterm infants

Bauer, Sofía; Eliakim, Alon; Pomeranz, Avishalom; Regev, Rivka; Litmanovits, Ita; Arnon, Shmuel; Huri, Haim; Dolfin, Tzipora

doi:10.1097/01.inf.0000065690.64686.c9

Cited by 64 publications

(51 citation statements)

References 17 publications

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“…The overall incidence of UTI in VLBW is reported at 8.1%, stratified as 5.7% for infants weighing 1000 to 1500 g and increasing to 12.5% for those <1000 g. 43 Depending on the organism, at least 100 colony-forming units (CFU) ml -1 from a suprapubic bladder aspiration or 10 000 CFU ml -1 from a sterile bladder catheterization is required for diagnosis, or less for Gram-negative organisms or fungi. 43,44 Evaluation for a UTI is not indicated for VLBW infants in the first 72 h of life. 45 However, beyond this period, when urine is no longer considered sterile, it should be included in the evaluation of a symptomatic infant.…”

Section: Types Of Infectionsmentioning

confidence: 99%

The changing spectrum of neonatal infectious disease

Plano

2010

J Perinatol

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To understand the changing spectrum of neonatal infectious disease, one must first be familiar with the history, the variety of organisms and the progression of change of neonatal infections over the years. As progressively more immature neonates are surviving, the spectrum of infectious disease has changed in response to current medical practice responsible for this success and to selective pressures on the microorganisms. The surviving very low birth weight infants are at a significant risk for contracting infections from this expanding repertoire of pathogens. Microorganisms once thought seemingly benign and nonpathogenic are now commonly accepted as pathogens and are among the most likely organisms to cause infections in this extremely vulnerable patient population. When considering the possible identity of infecting organisms and attempting to tailor specific therapies to decrease unwanted consequences, one must consider the level of maturity and the age of neonate, as well as the intensity of care necessary for a successful outcome. This brief review focuses primarily on the changing spectrum of bacterial and fungal infections and will not substantially address viral infections.

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Section: Types Of Infectionsmentioning

confidence: 99%

The changing spectrum of neonatal infectious disease

Plano

2010

J Perinatol

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“…1, 8 Bauer reported that the prevalance of UTI among late-onset sepsis neonates with birth weight =1000 grams was 12.2%, while in neonates with birth weight 1001-1500 grams was 5.2%. 8 In our study, UTI was found in 3 out of 9 subjects with birth weight <1500 grams and in 3 out of 17 subjects with birth weight 1500-2499 grams, while in neonates with birth weight 2500-3999 grams was only 1 out of 21 subjects.…”

Section: Discussionmentioning

confidence: 99%

“…7 Bauer et al reported 12.2% subjects with UTI among 279 late-onset sepsis neonates (gestational age of 26 ± 1.7 week). 8 Visser and Hall found 7.4% subjects with UTI from 189 neonates (gestational age 33.2 ± 1.1 weeks) who underwent sepsis evaluation for suspected late-onset sepsis. 4 Purniti reported UTI in 10 out of 35 preterm and 9 out of 52 term neonates with neonatal sepsis.…”

Section: Discussionmentioning

confidence: 99%

“…[1][2][3] The prevalence of UTI among late-onset sepsis neonates in developed countries varies from 7.4 to 25.3%, with higher rates in preterm infants. [4][5][6][7][8] UTI at very young age has the potential for lifelong morbidity. Progressive renal damage in early childhood may lead to hypertension and chronic renal failure later in life.…”

Section: Urinary Tract Infection Among Neonatal Sepsis Of Late-onset mentioning

confidence: 99%

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Urinary tract infection among neonatal sepsis of late-onset in Cipto Mangunkusumo Hospital

Amelia¹,

Amir²,

Trihono³

2016

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, MD, MM(Paed) association with neonatal sepsis. It is often difficult to identify whether UTI was the cause or the effect of bacteremia. 1-3 The prevalence of UTI among late-onset sepsis neonates in developed countries varies from 7.4 to 25.3%, with higher rates in preterm infants. [4][5][6][7][8] UTI at very young age has the potential for lifelong morbidity. Progressive renal damage in early childhood may lead to hypertension and chronic renal failure later in life. 2,9 The clinical manifestations of UTI in the neonatal period may vary and are nonspecific, as well as the sepsis itself. 1-3,10 Urinalysis and urine culture as well as lumbar puncture for late-onset neonatal sepsis are part of a full septic-work up, 10 but are not routinely done in our neonatal ward. It is important to recognize whether there is pyelonephritis in a neonate who shows clinical signs of sepsis in order to provide appropriate treatment. However, proper procedures in obtaining urine samples for culture are invasive and have potential risks for trauma and infection. 2,9 The objective of our study was to define the prevalence and microbiological pattern of UTI among neonates with late-onset sepsis in the neonatal ward of Cipto Mangunkusumo Hospital.T he urinary tract is a common site of infection in infants and young children. 1 Urinary tract infection (UTI) in neonates often occur in ABSTRACTBackground Urine culture, as part of a full septic work-up for

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“…Urinary tract infections occur in about 1% of term neonates, with a higher prevalence among preterm neonates. 6 Bacteria that commonly cause urinary tract infections, such as Escherichia coli, Klebsiella, and Enterobacter, travel from the gastrointestinal tract and anogenital area into the urinary tract. 7 In this case, L. lactis was thought to have come from the gastrointestinal tract after ingestion of the mother's breast milk.…”

Section: Discussionmentioning

confidence: 99%