Urinary Tract Stone Disease

Ishaq, Muhammad; Akhund, Israr Ahmed; Laghari, Maula Bux; Sabir, Muhammad

doi:10.29309/tpmj/2011.18.02.2060

Cited by 2 publications

(1 citation statement)

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“…However, in Asia, it affects around 1-5% of the population, while prevalent in 7-13% and 5-19% of people in North America and Europe, respectively. Pakistan is a hotspot for renal calculus disease, possibly having the highest incidence globally [3][4][5].…”

Section: Introductionmentioning

confidence: 99%

Safety and Efficacy of Mini-Percutaneous Nephrolithotomy (mini PCNL) in Pediatric Patients with Staghorn Stone: A Single Center Study in Pakistan

Tahir,

Bakar,

Khan

et al. 2024

Preprint

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Purpose This study aimed to evaluate the safety and efficacy of mini-percutaneous nephrolithotomy (mini-PCNL) in pediatric patients with staghorn stones in Pakistan. Methods The study was conducted at the Armed Forces Institute of Urology, Rawalpindi, Pakistan, from December 1, 2022, to June 1, 2023. A total of 140 participants were included in the study using a non-probability consecutive sampling technique. Inclusion criteria included male and female patients aged 3 months to 18 years with sterile urine cultures, while exclusion criteria included malrotation or ectopic pelvic kidneys, uncontrolled urinary tract infections, and comorbidities that contraindicated surgery. The study followed ethical approval and informed consent was obtained from all participants. Data collection involved recording patient demographics, surgical parameters, and postoperative outcomes. The procedures were performed using the Karl Storz Nagele minimally invasive PCNL system, and the Swiss Lithoclast Master was used to fragment the stones. Results The study found that mini-PCNL is a safe and effective treatment option for pediatric patients with staghorn stones, with a stone-free rate of 82.1% and a complication rate of 9.3%. Conclusion The study recommends mini-PCNL as a preferred treatment option for pediatric patients with staghorn stones due to its minimally invasive nature and lower complication rate compared to traditional PCNL. Overall, this study showed that mini-PCNL is a safe and effective therapeutic option for kidney stones in pediatric patients. Future research should be conducted using a wider population to generalize the results.

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Section: Introductionmentioning

confidence: 99%

Safety and Efficacy of Mini-Percutaneous Nephrolithotomy (mini PCNL) in Pediatric Patients with Staghorn Stone: A Single Center Study in Pakistan

Tahir,

Bakar,

Khan

et al. 2024

Preprint

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Rapid Real Time PCR Based Detection of Cell Count in Case of Urinary Tract Infection

Nandy

Thakur

Chaudhuri

2013

American Journal of Biochemistry and Biotechnology

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Microbial identification and antimicrobial susceptibility testing methods currently used in clinical microbiology laboratories require at least two to three days because they rely on the growth and isolation of micro-organisms. This long, but necessary, delay has enormous consequences on prophylactic usage of antimicrobial drugs. This study was an attempt to reduce this detection time span. Taq Man Real Time PCR has been used as an important tool in the differentiation of Gram nature of bacteria present in UTI patients that allows detection of spiked bacterial 16S rDNA from urine samples within a short span of 5h and also gives us the corresponding cell count of both/either Gram positive and negative organisms present. A standard curve was generated which was used to determine the cell count of control as well as patient samples. Detection could be done in the range of 10 3 to 10 6 cells/mL Patient samples screened clustered either in the allele 1 or allele 2 axes, depending on majority concentration of Gram nature of the microorganisms. The cell counts for control individuals were scattered within 0 to 10 2 , while very few in the range of 10 4 . The case was just reverse for patient group, where most of the points were scattered within 10 4 to 10 8 . Thus the optimal selection of appropriate antimicrobials (depending on the gram nature) by clinicians, will be gradually improved as an increasing number of rapid molecular diagnostic tools for the detection, identification and characterization of infectious agents become commercially available.

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Urinary Tract Stone Disease

Cited by 2 publications

References 0 publications

Safety and Efficacy of Mini-Percutaneous Nephrolithotomy (mini PCNL) in Pediatric Patients with Staghorn Stone: A Single Center Study in Pakistan

Safety and Efficacy of Mini-Percutaneous Nephrolithotomy (mini PCNL) in Pediatric Patients with Staghorn Stone: A Single Center Study in Pakistan

Rapid Real Time PCR Based Detection of Cell Count in Case of Urinary Tract Infection

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