Background: Urine color (UC) is affected by fluid intake and loss from the body. Critically ill patients are exposed to many stressors added to the fluid intake or loss that can disturb body fluids movement affecting the color of the excreted urine. Aim: To assess factors affecting change of the urine color as a hydration indicator among critically ill patients. Design: A descriptive research design was used. Setting: The study was conducted at three general intensive care units in the Teaching Main