Urogenitaltuberkulose in Deutschland

Abstract

Genitourinary tuberculosis (GUTB) usually results from the reactivation of old, dormant tuberculous diseases by pathogens of the Mycobacterium tuberculosis complex. The diagnosis of tuberculosis of the urinary tract is based on the case history, the finding of pyuria in the absence of infection as judged by culture on routine media and by radiological imaging. A positive yellow egg culture and/or histological analysis of biopsy specimens possibly combined with the polymerase chain reaction (PCR) is still required in most patients to establish a definitive diagnosis of GUTB. Antituberculous drug treatment is based on an initial 2 month intensive phase with three or four drugs daily followed by a 4 month continuation phase with only two drugs. Surgery as a treatment option in GUTB might be indicated in complicated urinary tuberculosis. After antituberculous treatment of GUTB a follow-up surveillance over 5 years is recommended. Although the incidence of GUTB in Germany is relatively low, it is still necessary to impart and deepen scientific knowledge of the diagnosis and therapy of GUTB.

REVIEW ARTICLES Genitourinary tuberculosis: historical and basic science review: past and present

“…In females the genital organs commonly affected are as follows: fallopian tube (95-100%), endometrium (50-60%), ovaries (20-30%), cervix (5-15%), myometrium (2.5%), and vulva/vagina (1%) [2, 4, 8, 9, 10]. …”

“…A significant differential diagnostic overlap requires maintaining a high index of suspicion for GUTB in both men and women. Diagnosis of is often delayed owing to the nonspecific nature of its presentation; therefore, a high degree of suspicion should be exercised and a systematic approach should be taken during investigation [4, 6, 8, 9, 10, 11]. …”

International Conference “Urogenital Infections and Tuberculosis” in Novosibirsk, Russia, Has Opened New Perspectives in the Fight against Tuberculosis

“…In developed countries, from 2% to 10% patients with PTB have also UGTB; in developing countries the proportion increases up to 15%–20% [ 3 ]. In Europe, UGTB is diagnosed more often in migrants, than in inhabitants [ 4 , 5 ]. About 20% of patients cured from PTB, had EPTB later, mostly UGTB [ 6 ].…”

Seuchengeschichte in der deutschsprachigen Urologie

“…In den Titeln einschlägiger, vielfach aufgelegter Lehrbücher [75,76] des Fachgebiets Urologie sowie neueren Übersichtsarbeiten [77][78][79][80][81][82][83][84] und Beiträgen in Lehr-und Handbüchern [85][86][87][88] sind Geschlechtskrankheiten, Tuberkulose und AIDS bedeutsam.…”