Urological Complications Following Live Donor Kidney Transplantation: Effect of Urinary Schistosomiasis

Abstract

Summar\/-Urological complications were studied in 310 live donor kidney transplants. All recipients and donors were investigated for urinary schistosomiasis by examining tissue obtained intra-operatively from the donor's ureter or the patient's bladder. Schistosomiasis was histologically documented in 76 cases (patient's bladder (46), donor's ureter (9), both (21)). The incidence of urological complications was 11/76 (1 5%) in the schistosomal group and 14/234 (6%) in the nonschistosomal group; this was statistically significant. Among the schistosomal patients, the site of infestation had no statistically significant effect on the incidence of urological complications. No deaths or graft losses were directly attributable either to these complications or to their surgical correction.

Urological complications after living‐donor renal transplantation

“…The potential impact of urinary bilharziasis has been addressed by several studies [29–33] with controversial conclusions. In the present series the rate of complications among patients with evidence of bilharziasis was 10%, while that among patients with no evidence was 7.4%; this difference was not statistically significant in the univariate analysis.…”

Renal transplantation: the impact of schistosomiasis

“…Urological complications were extensively assessed in a prospective study including 310 live‐donor kidney transplants [24]. All recipients and donors were investigated for urinary schistosomiasis by examining tissue obtained during surgery from the donor's ureter or patient's bladder.…”

“…No deaths or graft losses were directly attributable either to these complications or to their surgical correction. From that study it was concluded that the estimated frequency of urological complications of 15% among the schistosomal recipients remains acceptable and does not contraindicate renal transplantation, as it did not affect either patient or graft survival [24].…”

Urethral Stricture Caused by Schistosomiasis in a Renal Transplant Recipient

“…Urethral stricture is a common urological complication after renal transplantation, usually seen as a complication of catheterization or urinary tract infection 1 . We report a case of recurrent urethral stricture caused by schistosomiasis in a renal transplant recipient.…”

“…Schistosomiasis is common in patients with high‐risk water exposure in endemic areas including the Middle East, Africa and South America 1 . Chronic infection with Schistosoma haematobium is associated with an increased risk of bladder cancer, urinary tract infection and urological complications such as ureteric fistula and obstructive uropathy 1 . Complications are often silent and not detected until irreversible changes have occurred.…”