Urological complications of endemic schistosomiasis in school-children

Forsyth, D.M.; MacDonald, George

doi:10.1016/0035-9203(65)90078-7

Cited by 60 publications

(9 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Often these studies described the prevalence of S. haematobium, or the effects of treatment for schistosomiasis. Examples include the Msambweni project in Kenya from 1984-1992 (31–34,36,38), Malumfashi Endemic Research Project and other sites in Nigeria (25,44), and several studies in both Tanzania (20,22,23) and Mali (29,47,48). …”

Section: Resultsmentioning

confidence: 99%

Kidney disease among children in sub-Saharan Africa: systematic review

et al. 2014

View full text Add to dashboard Cite

The global burden of kidney disease is increasing, and several etiologies first begin in childhood. Risk factors for pediatric kidney disease are common in Africa, but data regarding its prevalence are lacking. We completed a systematic review of community-based studies describing the prevalence of proteinuria, hematuria, abnormal imaging, or kidney dysfunction among children in sub-Saharan Africa. Medline and Embase were searched. Five hundred twenty-three references were reviewed. Thirty-two references from 9 countries in sub-Saharan Africa were included in the qualitative synthesis. The degree of kidney damage and abnormal imaging varied widely: proteinuria 32.5% (2.2%-56.0%); hematuria 31.1% (0.6%-67.0%); hydronephrosis 11.3% (0.0%-38.0%), hydroureter 7.5% (0.0%-26.4%), major kidney abnormalities 0.1% (0.0%-0.8%). Serum creatinine was reported in four studies with insufficient detail to identify the prevalence renal dysfunction. A majority of the studies were performed in Schistosoma haematobium endemic areas. A lower prevalence of kidney disease was observed in the few studies from non-endemic areas. Published data on pediatric kidney disease in sub-Saharan Africa is highly variable and dependent on S. haematobium prevalence. More community-based studies are needed to describe the burden of pediatric kidney disease, particularly in regions where S. haematobium infection is non-endemic.

show abstract

Section: Resultsmentioning

confidence: 99%

Kidney disease among children in sub-Saharan Africa: systematic review

et al. 2014

View full text Add to dashboard Cite

show abstract

“…Common early signs include dysuria, proteinuria, and haematuria [95-111]. The development of urological abnormalities related to S. haematobium infection is associated with the intensity of infection [96,112-115]. Several epidemiological and clinical studies conducted in Zanzibar (Unguja and Pemba) and the mainland part of the country have reported high prevalences of S. haematobium and different types of morbidities associated with urogenital schistosomiasis across all age groups and gender (Table 2).…”

Section: Methodsmentioning

confidence: 99%

“…Several epidemiological and clinical studies conducted in Zanzibar (Unguja and Pemba) and the mainland part of the country have reported high prevalences of S. haematobium and different types of morbidities associated with urogenital schistosomiasis across all age groups and gender (Table 2). The common urogram abnormalities were calcified urinary bladder, calcified and distorted ureters, hydronephrosis and non-functioning kidney [96,112-116]. In addition, multiple or bilateral lesions were also identified, including calcified bladder, deformity of the ureter, hydronephrosis and non-functioning kidneys [112-116].…”

Section: Methodsmentioning

confidence: 99%

“…The common urogram abnormalities were calcified urinary bladder, calcified and distorted ureters, hydronephrosis and non-functioning kidney [96,112-116]. In addition, multiple or bilateral lesions were also identified, including calcified bladder, deformity of the ureter, hydronephrosis and non-functioning kidneys [112-116]. A direct relationship between intensity of infection and the abnormalities of the urinary tract was observed, in which calcified urinary bladders, deformed ureters and hydronephrosis were significantly more common in schoolchildren who had higher infection intensities (excreted >250 eggs/10ml of urine) [112-115].…”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Epidemiology and control of human schistosomiasis in Tanzania

et al. 2012

View full text Add to dashboard Cite

In Tanzania, the first cases of schistosomiasis were reported in the early 19th century. Since then, various studies have reported prevalences of up to 100% in some areas. However, for many years, there have been no sustainable control programmes and systematic data from observational and control studies are very limited in the public domain. To cover that gap, the present article reviews the epidemiology, malacology, morbidity, and the milestones the country has made in efforts to control schistosomiasis and discusses future control approaches. The available evidence indicates that, both urinary and intestinal schistosomiasis are still highly endemic in Tanzania and cause significant morbidity.Mass drug administration using praziquantel, currently used as a key intervention measure, has not been successful in decreasing prevalence of infection. There is therefore an urgent need to revise the current approach for the successful control of the disease. Clearly, these need to be integrated control measures.

show abstract

“…Deur die gebruik van 'n sensitiewe fi ltrasietegniek het Warren et al 4 ' n relatiewe lae daaglikse variasie aangetoon en het hierdie outeur tot bepaalde gevolgtrekkings ten opsigte van die gebruike en beperkings van enkelmonsterondersoeke, indien dit vir intensiteitsbepalings aangewend word, gekom. Die omstandigheid dat die getal eiers wat op 'n bepaalde tyd in die urine teenwoordig is, as kriterium vir aspekte soos die graad van morbiditeit, 8 prevalensie, intensiteit, wurmbelading, 9 genitale letsels, 10 en urienwegsiekte 11,12 gebruik word, kan misleidend wees omdat die getal eiers soos reeds genoem, varieer en afl eidings dus moeilik hiervan gemaak kan word. Volgens Schutte et al, 13 het herhaalde versamelings oor kort periodes gedurende die algemeen aanvaarde piekperiode die variasie in eierekskresie verder uitgelig en stel hulle voor dat hierdie data vir statistiese analises, logaritmies aangepas word.…”

Section: Inleidingunclassified