Urological complications of endemic schistosomiasis in schoolchildren

MacDonald, George; Forsyth, D.M.

doi:10.1016/0035-9203(68)90003-5

Cited by 14 publications

(4 citation statements)

References 13 publications

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“…Earlier studies gave conflicting views on the regression of urinary tract pathology: observing gross lesions by intravenous pyelography, several studies reported that the resolution of uropathy after treatment was very limited. [17][18][19] Others found that many lesions were reversible especially in children. [20][21][22] The limited resolution observed in the 1960s could possibly be due to the lower efficacy of the drug available at that time.…”

Section: Discussionmentioning

confidence: 99%

The public health significance of urinary schistosomiasis as a cause of morbidity in two districts in Mali.

Traoré

Traoré²,

Kardorff³

et al. 1998

The American Journal of Tropical Medicine and Hygiene

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Schistosoma haematobium-related morbidity was studied in the perennial irrigation area of Office du Niger and the small reservoirs area of Plateau Dogon in Mali. Questionnaire, clinical, parasitologic, and ultrasound examination data were collected from 1,041 individuals at the baseline survey in 1991; 705 were reexamined one year after treatment. At baseline, the overall prevalence of S. haematobium infection was 55.2%; half of those infected had no clinical symptoms and 30% had pathologic lesions. Both infection and morbidity were more frequent in children than in adults, with a peak prevalence at 7-14 years of age. The rates of lesions were more than twice as high in those heavily infected as in lightly infected individuals. Reagent strip testing for microhematuria was more sensitive in detecting individuals with pathologic lesions than in detecting individuals with infection. One year after treatment with praziquantel, more than 80% of the urinary tract lesions had cleared. It is concluded that S. haematobium-related morbidity is frequent in Mali, but passive case detection for treatment would not cover a great deal of early stages of the disease; active intervention using reagent strip testing for microhematuria at the most peripheral levels would be an efficient system for morbidity control and monitoring of control operations.

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Section: Discussionmentioning

confidence: 99%

The public health significance of urinary schistosomiasis as a cause of morbidity in two districts in Mali.

Traoré

Traoré²,

Kardorff³

et al. 1998

The American Journal of Tropical Medicine and Hygiene

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“…Common early signs include dysuria, proteinuria, and haematuria [95-111]. The development of urological abnormalities related to S. haematobium infection is associated with the intensity of infection [96,112-115]. Several epidemiological and clinical studies conducted in Zanzibar (Unguja and Pemba) and the mainland part of the country have reported high prevalences of S. haematobium and different types of morbidities associated with urogenital schistosomiasis across all age groups and gender (Table 2).…”

Section: Methodsmentioning

confidence: 99%

“…In addition, multiple or bilateral lesions were also identified, including calcified bladder, deformity of the ureter, hydronephrosis and non-functioning kidneys [112-116]. A direct relationship between intensity of infection and the abnormalities of the urinary tract was observed, in which calcified urinary bladders, deformed ureters and hydronephrosis were significantly more common in schoolchildren who had higher infection intensities (excreted >250 eggs/10ml of urine) [112-115]. Similar findings were reported in Unguja and the observed urological complications were associated with high intensity of infection [112-115].…”

Section: Methodsmentioning

confidence: 99%

“…A direct relationship between intensity of infection and the abnormalities of the urinary tract was observed, in which calcified urinary bladders, deformed ureters and hydronephrosis were significantly more common in schoolchildren who had higher infection intensities (excreted >250 eggs/10ml of urine) [112-115]. Similar findings were reported in Unguja and the observed urological complications were associated with high intensity of infection [112-115]. Ultrasonographical surveys in the south east of the country, the areas endemic for S. haematobium, produced similar results, but the overall rate of urological abnormalities was high [96].…”

Section: Methodsmentioning

confidence: 99%

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Epidemiology and control of human schistosomiasis in Tanzania

et al. 2012

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In Tanzania, the first cases of schistosomiasis were reported in the early 19th century. Since then, various studies have reported prevalences of up to 100% in some areas. However, for many years, there have been no sustainable control programmes and systematic data from observational and control studies are very limited in the public domain. To cover that gap, the present article reviews the epidemiology, malacology, morbidity, and the milestones the country has made in efforts to control schistosomiasis and discusses future control approaches. The available evidence indicates that, both urinary and intestinal schistosomiasis are still highly endemic in Tanzania and cause significant morbidity.Mass drug administration using praziquantel, currently used as a key intervention measure, has not been successful in decreasing prevalence of infection. There is therefore an urgent need to revise the current approach for the successful control of the disease. Clearly, these need to be integrated control measures.

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Obstructive renal failure in bilharziasis

Dukes¹,

Mynors²

1970

Journal of British Surgery

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The management is considered of 10 patients who presented in advanced uraemia due to ureteric strictures consequent upon schistosomal infestation, 4 of whom recovered. In view of the length of ureter involved in the disease process it is highly probable that definitive by‐pass of the obstruction will require a replacement procedure, such as an ileal loop. It seems likely that improved survival rates will be obtained where energetic measures are pursued aimed at the support of the patient and early relief of the obstruction, even if this can only be performed under local anaesthesia owing to the condition of the patient.

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Urological complications of endemic schistosomiasis in schoolchildren

Cited by 14 publications

References 13 publications

The public health significance of urinary schistosomiasis as a cause of morbidity in two districts in Mali.

The public health significance of urinary schistosomiasis as a cause of morbidity in two districts in Mali.

Epidemiology and control of human schistosomiasis in Tanzania

Obstructive renal failure in bilharziasis

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