Urological Manifestations of Obstructive Sleep Apnea Syndrome: A Review of Current Literature

Dagur, Gautam; Warren, Kelly; Ambroise, Sedrick; Imhof, Reese L.; Khan, Sardar

doi:10.21767/2172-0479.100022

Cited by 2 publications

(1 citation statement)

References 109 publications

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“…Together, hypoxia and sleep fractionation due to partial or full arousal when breathing arrests, cause daytime sleepiness, headaches, difficulty concentrating, forgetfulness, irritability and depression. Left untreated, IH resulting from OSA is linked to many serious conditions, encompassing hypertension, heart attack, stroke and diabetes (Dagur and Warren, 2015; International Diabetes Federation, 2008).…”

Section: Causes Of Lutsmentioning

confidence: 99%

Links between lower urinary tract symptoms, intermittent hypoxia and diabetes: Causes or cures?

Abler

Vezina

2018

Respiratory Physiology & Neurobiology

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Bothersome lower urinary tract symptoms (LUTS) manifest as urinary frequency, urgency, incontinence and incomplete bladder emptying. Existing treatments ameliorate but do not eliminate most symptoms, leading to financial and personal burdens attributable to sustained medical therapies that may last a lifetime. The purpose of this review is to highlight evidence of causal associations between LUTS and several common comorbidities, including intermittent hypoxia (IH) concomitant with obstructive sleep apnea (OSA), obesity, metabolic syndrome and type 2 diabetes. Links between these conditions, including therapies targeted to co-occurring complications that have demonstrated benefits for LUTS, suggest compelling avenues of research and also underscore critical gaps in understanding the mechanisms underlying urinary dysfunction. These gaps are prominent in the IH field, where an acknowledged link between OSA and LUTS has gone largely uninvestigated. New tools, models, or reappropriation of existing ones, especially rodent models, is required to parse the associations between IH/OSA, LUTS and obesity/diabetes and to elucidate their underlying, and potentially shared, etiologies.

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Section: Causes Of Lutsmentioning

confidence: 99%

Links between lower urinary tract symptoms, intermittent hypoxia and diabetes: Causes or cures?

Abler

Vezina

2018

Respiratory Physiology & Neurobiology

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Habitual snoring and primary enuresis in children

Mahara

Ramayani

Effendy³

et al. 2018

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Background Obstructive sleep-disordered breathing is assumed to be associated with primary enuresis in children. Prolonged enuresis may cause developmental and emotional disorders, as well as poor school performance. Objective To determine the relationship between habitual snoring and primary enuresis in children. Methods A cross-sectional study was conducted in Muara Batang Gadis District, North Sumatera in April 2016. Subjects were children aged 5-14 years. The Sleep Disturbance Scale for Children (SDSC) questionnaire was used to measure the symptoms of sleep disordered breathing; the International Association Child and Adolescent Psychiatry and Allied Professions (IACAPAP) questionnaire was used to assess for the presence of primary enuresis. The questionnaires were answered by the children’s parents. Data were analyzed using Chi-square and logistic regression tests. A P value of <0.05 was considered to be statistically significant. Results The mean age of 110 participants was 9.23 (SD 2.16) years. Twenty-seven (24.5%) subjects snored more than three nights per week (habitual snorers) and 18 (16.4%) subjects had primary enuresis. There was a significantly higher percentage of habitual snorers with enuresis than that of snorers without enuresis (55.5% vs. 18.4%, respectively) (P<0.05). Conclusion There is a significant relationship between habitual snoring and primary enuresis.

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Urological Manifestations of Obstructive Sleep Apnea Syndrome: A Review of Current Literature

Cited by 2 publications

References 109 publications

Links between lower urinary tract symptoms, intermittent hypoxia and diabetes: Causes or cures?

Links between lower urinary tract symptoms, intermittent hypoxia and diabetes: Causes or cures?

Habitual snoring and primary enuresis in children

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