Urothelial bladder tumour in childhood: A report of two cases and a review

Abstract

Urothelial bladder tumour in childhood is extremely rare, and almost all the reported cases have been low-grade tumours with a favourable outcome. Here we review 57 reports comprising 127 cases, and we report two new cases.

Urothelial bladder carcinoma in childhood: a case report

“…A higher ki67 expression level in elderly than in young patients was reported and could explain the better outcome in pediatric population [ 9 ]. The main treatment modality is transurethral resection (TUR) of tumor because of low grade of malignancy and low recurrence rate [ 10 ]. Because of limited data, no standards exist for the use of adjuvant medical therapy or intravesical immunotherapy.…”

“…High-grade bladder carcinomas can be lethal and require more aggressive treatment and monitoring when compared to low-grade carcinomas [ 4 ]. High ki67 expression and low cycline D1 were associated with a greater risk of recurrence in young patients [ 10 ]. By searching in the recent literature of pediatric BC cases, 82 cases were found ( Table 1 ).…”

Urothelial Carcinoma in Pediatric Patient

“…There is no evidence for adjuvant therapy small in a pediatric age group. Rifat et al [5] have mentioned that TURBT along with cystoscopic followup was the most common modality of treatment in stage-Ta urinary bladder tumor in review of 127 cases of a pediatric age group. Korrect et al [6] have performed partial cystectomy for a high-grade tumor in view of risk of perforation of the pediatric bladder.…”

Bladder Papilloma As A Rare Cause Of Urogenital Bleeding In A Prepubertal Girl

“…1,2 Vaginal, urethral, bladder lesions, foreign body, hormonal problems, vaginal-urinary infections, and tumors are among the causes of bleeding. [3][4][5] In cases, detailed anamnesis is important. An external and internal genital examination and hormonal studies, pelvic ultrasonography should be…”