Urothelial carcinoma arising within a congenital bladder diverticulum in an adult male: A rare case report and literature review

Rahman, Seif-Aldin Abdul; Muhammad, Ibrahim; Abdulrahman, Ali; Raslan, Khidr; Alshehabi, Zuheir

doi:10.1016/j.amsu.2022.103666

Cited by 3 publications

(1 citation statement)

References 24 publications

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“…Hutch diverticula cause significant vesicoureteral reflux because they distort the ureterovesical junction 4,5 . Primary congenital diverticula have been linked to the connective tissue disorders known as Ehlers-Danlos types IV, V, and IX, which are said to cause the diverticula to rupture spontaneously 6,7 .…”

Section: Introductionmentioning

confidence: 99%

Resultados clínicos y urodinámicos en divertículos vesicales primarios pediátricos: un estudio comparativo

Karaaslan,

Kuzdan

2024

CIRU

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Objective: This study aimed to compare the effects of bladder diverticula smaller than 30 (SD) mm and larger than 30 mm (LD) on bladder functions and urodynamics. Materials and methods: Our retrospective analysis involved a cohort of 40 pediatric patients diagnosed with primary bladder diverticula. Results: The predicted mean bladder capacity (MBC) was 197.7 ± 95.8 mL, whereas the observed MBC was lower at an average of 170.1 ± 79.6 mL. This indicates that the observed MBC was 88.2 ± 12.9% of the predicted value (percentage). The mean diverticula diameter recorded was 33 ± 19.5 mm, and the diverticula to MBC ratio were calculated to be 0.25 ± 0.18. The distribution of urinary tract infections (UTIs) differed significantly between the groups (p < 0.001). Upper UT dilatation was significantly more common in the LD group (60%, n = 12) than in the SD group (15%, n = 3) (p = 0.003). The mean detrusor pressure (P[detrusor]) was significantly higher in the LD group (137.2 ± 24.1 cm H 2 O) than in the SD group (63.9 ± 5.8 cm H 2 O) (p = 0.001). In addition, the mean peak flow rate (Q max ) was significantly higher in the SD group (20.7 ± 7.9 mL/s) compared to the LD group (12.7 ± 3.8 mL/s) (p < 0.001). Conclusion: Bladder diverticula size is a significant factor in the clinical presentation and management of primary bladder diverticula in pediatric patients.

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Section: Introductionmentioning

confidence: 99%

Resultados clínicos y urodinámicos en divertículos vesicales primarios pediátricos: un estudio comparativo

Karaaslan,

Kuzdan

2024

CIRU

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Diagnosis and management of intradiverticular bladder tumours: A pooled analysis of 498 cases

Katsimperis

Tzelves

Bellos

et al. 2022

Arch Ital Urol Androl

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Objective: Intradiverticular bladder tumors (IDBT) are uncommon clinical entities. We reviewed the literature for clinical presentation, diagnosis and therapeutic options to establish recommendations for diagnostic and therapeutic management. Methods: Bibliographic research was performed using PubMed from database inception until October 15, 2022. A pooled analysis was performed of 498 patients with IDBT presented in the literature. The evaluation included patient sex, age, diagnostic methods, symptoms, localization of the tumor, tumor staging, tumor histopathology, treatment, and the presence of recurrence. To express results, descriptive statistics were used appropriately. Results: The mean age at diagnosis was 64.81 years (range 49 days to 84 years). The ratio between men and women was ≈ 24:1, suggesting a male predominance (85% male, 3.6% female). The most common presenting symptom was gross hematuria (60.88%). Most of the patients had cystoscopy (56.85%) and intravenous or computed tomography urography (52.01%). Regarding tumor staging, most of the patients were diagnosed with pT1 tumors. For the histopathology of IDBT, 87.95% of the specimens were transitional cell carcinomas and in 10.84% there were concomitant CIS. Regarding the treatment, radical cystectomy was chosen in 34.34%, partial cystectomy in 26.66%, diverticulectomy in 15.95% and transurethral resection of bladder tumour (TURBT) in 16.36% of the patients.Conclusions: Most common diagnostic tool for IDBT seems to be cystoscopy followed by computerized tomography urogram. Due to the absence of muscle layer in the diverticulum and the highgrade histology of most of them at diagnosis, cystectomy is the first therapeutic choice. However, for patients that are not considered appropriate candidates or for those presenting with lowgrade and low volume tumors, TURBT is a good option.

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Clinical Presentation, Tumor Characteristics, and Management of Intradiverticular Transitional Cell Carcinoma of the Urinary Bladder: A Systematic Review

Aijaz,

Farooqi Baloch,

Faiz

et al. 2024

Cureus

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Urothelial carcinoma arising within a congenital bladder diverticulum in an adult male: A rare case report and literature review

Cited by 3 publications

References 24 publications

Resultados clínicos y urodinámicos en divertículos vesicales primarios pediátricos: un estudio comparativo

Resultados clínicos y urodinámicos en divertículos vesicales primarios pediátricos: un estudio comparativo

Diagnosis and management of intradiverticular bladder tumours: A pooled analysis of 498 cases

Clinical Presentation, Tumor Characteristics, and Management of Intradiverticular Transitional Cell Carcinoma of the Urinary Bladder: A Systematic Review

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