Urtica dioica L. leaf chemical composition: A never-ending disclosure by means of HR-MS/MS techniques

Brahmi-Chendouh, Nabila; Piccolella, Simona; Nigro, Ersilia; Hamri-Zeghichi, Sabrina; Madani, Khodir; Daniele, Aurora; Pacifico, Severina

doi:10.1016/j.jpba.2021.113892

Cited by 9 publications

(4 citation statements)

References 34 publications

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“…Oxylipins polyunsaturated fatty acids are an important dietary compounds, and can be found in edible fruits by HPLC orbitrap mass spectrometry [47] and also can be found in useful plants [48] and lichens [49]. In this study, several fatty acids including saturated fats and oxylipins were found using this technique in Sticta lichens.…”

Section: Lipidsmentioning

confidence: 69%

Phylogenetic Studies and Metabolite Analysis of Sticta Species from Colombia and Chile by Ultra-High Performance Liquid Chromatography-High Resolution-Q-Orbitrap-Mass Spectrometry

et al. 2022

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Eleven species of lichens of the genus Sticta, ten of which were collected in Colombia (S. pseudosylvatica S. luteocyphellata S. cf. andina S. cf. hypoglabra, S. cordillerana, S. cf. gyalocarpa S. leucoblepharis, S. parahumboldtii S. impressula, S. ocaniensis) and one collected in Chile (S. lineariloba), were analyzed for the first time using hyphenated liquid chromatography with high-resolution mass spectrometry. In the metabolomic analysis, a total of 189 peaks were tentatively detected; the analyses were divided in five (5) groups of compounds comprising lipids, small phenolic compounds, saturated acids, terpenes, and typical phenolic lichen compounds such as depsides, depsidones and anthraquinones. The metabolome profiles of these eleven species are important since some compounds were identified as chemical markers for the fast identification of Sticta lichens for the first time. Finally, the usefulness of chemical compounds in comparison to traditional morphological traits to the study of ancestor–descendant relationships in the genus was assessed. Chemical and morphological consensus trees were not consistent with each other and recovered different relationships between taxa.

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Section: Lipidsmentioning

confidence: 69%

Phylogenetic Studies and Metabolite Analysis of Sticta Species from Colombia and Chile by Ultra-High Performance Liquid Chromatography-High Resolution-Q-Orbitrap-Mass Spectrometry

et al. 2022

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“…In light of the above, the NaDES-based samples were at first tested on the human colorectal adenocarcinoma (Caco-2) cell line to obtain preliminary information about their capability to affect the cell mitochondrial redox activity (RAI), which represents the first sign of cell suffering due to cytotoxicity. Indeed, this cell line has been widely employed as a model of the intestinal epithelial barrier, especially in studies dealing with the absorption of dietary components [ 22 ].…”

Section: Resultsmentioning

confidence: 99%

“…In line with previous research, the DPPH and ABTS methods were herein employed to further corroborate chemical composition data before and after simulated digestion, as they are able to provide accurate results strongly related to the sample chemical features. In fact, these tests are based on a mixed mode of action of a sample in transferring a single electron (SET) and/or a hydrogen atom (HAT) to the radical probe, resulting in its neutralization [ 22 , 40 ]. Thus, only compounds that possess active groups (e.g., catechol moieties in simple phenols and polyphenols) are able to react.…”

Section: Resultsmentioning

confidence: 99%

Ready-to-Use Nutraceutical Formulations from Edible and Waste Organs of Algerian Artichokes

Brahmi-Chendouh

Piccolella

Gravina

et al. 2022

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Edible, plant-derived foodstuffs are recognized as precious sources of polyphenol compounds, whose consumption has proven to have multiple beneficial effects on human health. However, the awareness that cooking processes are able to induce quali-quantitatively changes in their native occurrence and that their bioavailability after food ingestion is poor led the research to move toward the preparation of nutraceutical supplements aimed at maximizing their content by effective extractive techniques and protecting them from degradation. The present work fits into this context, proposing a green, ready-to-use formulation of capitula, stems, and leaves of Algerian artichokes, in which natural deep eutectic solvents were exploited as extracting solvents but not removed at the end of the process. MTT test on the Caco-2 cell line highlighted that mitochondrial redox activity inhibition was absent below the 50 µg/mL tested dose. Simulated in vitro digestion was used as a predictive model for formulation bioaccessibility, where the joint approach with UHPLC-HRMS techniques allowed to define the release of each polyphenol from the investigated matrices. The capitula-based sample was the richest one in flavonoids, especially luteolin and apigenin glycosides, which survived in the intestinal digesta. On the contrary, simple phenols characterized the stem sample, whose release was mainly in the gastric chyme.

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“…More specifically, Grauso et al [99] found that stinging nettle extracts contained two pentacyclic triterpenols αand β-amyrin in the non-polar fraction, whereas, in the polar extract, large amounts of choline were found. Brahmi-Chendouh et al [100] reported that hydroxycinnamic acid derivatives next to C-glycosylated flavones were the most representative constituents in stinging nettle leaves. However, taxa belonging to Urtica dioica appear to have similar metabolite compositions and, therefore, similar pharmacological properties [84].…”

Section: Nettle Phytochemistrymentioning

confidence: 99%

Nettle, a Long-Known Fiber Plant with New Perspectives

et al. 2022

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The stinging nettle Urtica dioica L. is a perennial crop with low fertilizer and pesticide requirements, well adapted to a wide range of environmental conditions. It has been successfully grown in most European climatic zones while also promoting local flora and fauna diversity. The cultivation of nettle could help meet the strong increase in demand for raw materials based on plant fibers as a substitute for artificial fibers in sectors as diverse as the textile and automotive industries. In the present review, we present a historical perspective of selection, harvest, and fiber processing features where the state of the art of nettle varietal selection is detailed. A synthesis of the general knowledge about its biology, adaptability, and genetics constituents, highlighting gaps in our current knowledge on interactions with other organisms, is provided. We further addressed cultivation and processing features, putting a special emphasis on harvesting systems and fiber extraction processes to improve fiber yield and quality. Various uses in industrial processes and notably for the restoration of marginal lands and avenues of future research on this high-value multi-use plant for the global fiber market are described.

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Urtica dioica L. leaf chemical composition: A never-ending disclosure by means of HR-MS/MS techniques

Cited by 9 publications

References 34 publications

Phylogenetic Studies and Metabolite Analysis of Sticta Species from Colombia and Chile by Ultra-High Performance Liquid Chromatography-High Resolution-Q-Orbitrap-Mass Spectrometry

Phylogenetic Studies and Metabolite Analysis of Sticta Species from Colombia and Chile by Ultra-High Performance Liquid Chromatography-High Resolution-Q-Orbitrap-Mass Spectrometry

Ready-to-Use Nutraceutical Formulations from Edible and Waste Organs of Algerian Artichokes

Nettle, a Long-Known Fiber Plant with New Perspectives

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