“…The role of pyrogenic suhstances could he excluded (20). Sensitivity reactions to gel or to gelatin ol the repository preparations could not be found in a single case (24,13,(44)(45), but Jf^est (44) describes a local reaction due to the phenol antiseptic. To a highly purified (Cortieotropin Ai) preparation no reactions could be observed in patients not tolerating the crutler Carboxycc!Iulo/.e (C()C)-purified ACTH (44).…”