Urticaria and angioedema

Mathews, Kenneth P.

doi:10.1016/0091-6749(83)90042-8

Cited by 79 publications

(29 citation statements)

References 46 publications

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“…The case presented here shows that no clear evidence connects IRBRAO with ernbolization or hypercoagulable statc. The clinical course of our patient is unique since it is associated with urticarial rash, a symptom not previously described in IRBRAO, but known to be associated with systemic vasculitis (Mathews 1983). The retinal vascular leakage seen in fluorescein angiogram may add to the vasculitis etiologic nature of this disease.…”

Section: Discussionmentioning

confidence: 80%

Urticaria in idiopathic bilateral recurrent branch retinal arterial occlusion

Barak

Ferencz

Freund

et al. 1997

Acta Ophthalmologica Scandinavica

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ABSTRACT. Idiopathic bilateral recurrent branch retinal arterial o c c . s i o n (IBRBRAO) is a rare syndrome characterized by migraine headaches, tinnitus, vertigo, hearing loss, and recurrent branch retinal artery occlusion of unknown etiology. Affected patients frequently undergo a wide range of medical evaluation and have no apparent pathologic findings. We present here a case of IBRBRAO, associated with urticaria1 rash, not described in this syndrome in previous publications.Key words: urticaria -thrombosis -retinal artery.Acta Ophthalmol. Scand. 1997: 75: 107-108 Case ReportA 35-year-old woman was admitted because of severe dizziness and decreased vision in her left eye. She was a healthy individual, not taking any medication or contraceptives. O n e year before her hospitalization she had suffered from migraine headaches that responded to propanolol treatment and resolved after a few weeks. Two months before her hospitalization, while not taking any medication, she started to suffer from diffuse urticarial rash. She responded to treatment with steroids, but a recurrency occurred when the dose was tapered to below 40 mg/day of prednisone. When hospitalized she complained of vertigo, and audio metric tests showed sensorimotor hearing loss in her right ear. Eye examination revealed a visual acuity of 6 / 6 (20/20) OU. Fundus examination of both eyes revealed areas of ischemic whitening of the retina sparing the fovea. There was no periartcrial sheathing. Fluorescein angiography revealed a multifocal arterial occlusion surrounded by focal areas of capillary non perfusion (Fig. 1).

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Section: Discussionmentioning

confidence: 80%

Urticaria in idiopathic bilateral recurrent branch retinal arterial occlusion

Barak

Ferencz

Freund

et al. 1997

Acta Ophthalmologica Scandinavica

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“…When they affect the respiratory, cardiovascular or gastrointestinal systems, it is called anaphylaxis. 3,[5][6][7] Episodes may occur daily or at irregular intervals, 1,2,4 can recur for an indefi nite time 3 and are considered chronic when the clinical picture persists for six weeks or more. 1,3,4,[7][8][9][10][11][12][13][14][15] Urticaria-angioedema can attack at any age and particularly affects middle-aged women.…”

Section: Introductionmentioning

confidence: 99%

“…3,[5][6][7] Episodes may occur daily or at irregular intervals, 1,2,4 can recur for an indefi nite time 3 and are considered chronic when the clinical picture persists for six weeks or more. 1,3,4,[7][8][9][10][11][12][13][14][15] Urticaria-angioedema can attack at any age and particularly affects middle-aged women. [1][2][3][4]6,8,10,[12][13][14]16,17 It is estimated that between 12% and 25% of the general population have already had at least one urticaria-angioedema episode 16,17 and that the prevalence among dermatological patients is around 1.85%.…”

Section: Introductionmentioning

confidence: 99%

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Sociodemographic and clinical characteristics, causal factors and evolution of a group of patients with chronic urticaria-angioedema

et al. 2007

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CONTEXT AND OBJECTIVE: Chronic urticaria-angioedema is a common, multiple-cause complaint. The aim was to investigate the sociodemographic and clinical characteristics, causal and aggravating factors and evolution of urticaria-angioedema. DESIGN AND SETTING: This was a descriptive prospective study carried out at the Dermatology outpatient clinic of Faculdade de Medicina de Botucatu, Universidade Estadual Paulista (Unesp). METHODS: A total of 125 patients with chronic urticaria-angioedema were evaluated to obtain sociodemographic data, anamnesis, dermatological and general clinical data and laboratory data, emphasizing causal and aggravating factors and complaint evolution. RESULTS: Chronic urticaria-angioedema occurred mainly in females (mean age: 35 years), but also in men (mean age: 32 years). White color and living in urban areas also predominated. There was no preferential time for symptoms to appear, and nighttime was the most commonly reported time for clinical worsening. Around half of the patients had urticaria associated with angioedema. There were no associated factors in most of the cases, and stress was the most commonly reported aggravating factor. The cause was ascertained in 37.6% of our cases. The mean duration of follow-up was 11.7 months. Around 60% of the patients evolved with the problem under control, 32% improved, 9% had no change in dermatological condition and only one patient worsened. CONCLUSIONS: Chronic urticaria-angioedema was more common among middle-aged women. It is a long-term disease, and its cause was explained in about one-third of the patients. Half of the patients presented disease control after treatment lasting an average of approximately one year.

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“…Several publications have reported that about 20% of the general population will experience urticaria, angioedema, or both at some time during their life: [1,2] 40% of these patients will have urticaria and angioedema, 40% will have urticaria without angioedema, and 11-20% will have angioedema without urticaria. Urticaria was first recognized as a distinct nosological entity by Hippocrates.…”

Section: Epidemiology Definitions and Clinical Findingsmentioning

confidence: 99%

Acute Urticaria and Angioedema

Frigas

Park

2009

American Journal of Clinical Dermatology

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Urticaria is defined as wheals consisting of three features: (i) central swelling of various sizes, with or without surrounding erythema; (ii) pruritus or occasional burning sensations; and (iii) the skin returning to normal appearance, usually within 1-24 hours. Angioedema is defined as: (i) abrupt swelling of the lower dermis and subcutis; (ii) occasional pain instead of pruritus; (iii) commonly involving the mucous membranes; and (iv) skin returning to normal appearance, usually within 72 hours. Acute urticaria and angioedema is defined by its duration (<6 weeks) compared with chronic urticaria and angioedema. The most common causes are infections, medications, and foods. The best tools in the evaluation of these patients are a comprehensive history and physical examination. There are a variety of skin conditions that may mimic acute urticaria and angioedema and the various reaction patterns associated with different drugs. Oral antihistamines are first-line treatment. In the event of a life-threatening reaction involving urticaria with angioedema, epinephrine may be needed to stabilize the patient. This review focuses on the value of a comprehensive clinical evaluation at the onset of symptoms. It underscores the importance of coordination of care among physicians, and the development of an action plan for evidence-based investigations, diagnosis, and therapy.

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Urticaria and angioedema

Cited by 79 publications

References 46 publications

Urticaria in idiopathic bilateral recurrent branch retinal arterial occlusion

Urticaria in idiopathic bilateral recurrent branch retinal arterial occlusion

Sociodemographic and clinical characteristics, causal factors and evolution of a group of patients with chronic urticaria-angioedema

Acute Urticaria and Angioedema

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