US Population Estimates of Health and Social Outcomes 5 Years After Rehabilitation for Traumatic Brain Injury

Corrigan, John; Cuthbert, Jeffrey P.; Harrison-Felix, Cynthia; Whiteneck, Gale G.; Bell, Jeneita M.; Miller, A. Cate; Coronado, Victor G.; Pretz, Christopher R.

doi:10.1097/htr.0000000000000020

Cited by 171 publications

(146 citation statements)

References 16 publications

Supporting

Mentioning

134

Contrasting

Unclassified

Order By: Relevance

“…Seel and colleagues [12] demonstrated that 27% of individuals with TBI met diagnostic criteria for MDD based on symptoms endorsed on the Neurobehavioural Functioning Inventory [7]. Five years after TBI, depression may be most prevalent for individuals aged 40 to 49 years relative to younger or older people [13].…”

Section: Structured Clinicalmentioning

confidence: 99%

Prevalence of suicidal behaviour following traumatic brain injury: Longitudinal follow-up data from the NIDRR Traumatic Brain Injury Model Systems

et al. 2016

View full text Add to dashboard Cite

Section: Structured Clinicalmentioning

confidence: 99%

Prevalence of suicidal behaviour following traumatic brain injury: Longitudinal follow-up data from the NIDRR Traumatic Brain Injury Model Systems

et al. 2016

View full text Add to dashboard Cite

“…Studies show that patients leaving hospitals against medical advice after TBI had higher rates of readmission 12,13 . Corrigan and colleagues (2014) 14 pointed out that age-specific interventions are needed to reduce post-acute inpatient rehabilitation mortality in TBI. For patients with stroke, Slocum and colleagues (2006) 15 found that age and functional status were better predictors of hospital readmission across nine years compared to medical comorbidities; however, such age-specific association remains unclear for the TBI population.…”

Section: Introductionmentioning

confidence: 99%

Effects of Age and Sex on Hospital Readmission in Traumatic Brain Injury

Karmarkar

Adhikari

et al. 2018

Archives of Physical Medicine and Rehabilitation

View full text Add to dashboard Cite

Objective To investigate the impact of age and sex on 30-, 60- and 90-day hospital readmission after acute hospital discharge for individuals with traumatic brain injury (TBI). Design Retrospective cohort study. Setting Acute hospitals and post-acute discharge settings Participants From the 2013 Nationwide Readmissions Database, we retrieved information on 52,877 individuals with diagnosis-related group codes of TBI. We included only those alive at index acute discharge and excluded those discharged with same-day readmission. We divided our sample into four age groups: 18-40, 41-65, 66-75 and 76+ years old. Interventions NA. Main Outcome Measure(s) All-cause hospital readmission. Results Sex differences in 30-, 60- and 90-day hospital readmission were found for all age groups (all p<.05). The largest sex differences in hospital readmission were in the two oldest groups (66-75, 76+). For both sexes, the oldest group (76+) had the highest adjusted 90-day readmission risk [e.g., 90-day readmission: Odds Ratio (OR) = 2.32 (2.01-2.69) for males; OR=1.96 (1.59-2.43) for females]. Among those readmitted within 90 days, the youngest group (18-40 years) had the highest cumulative readmission percent (35% for both sexes) within the first week post-hospital discharge. Conclusion Age and sex were significantly associated with hospital readmission during the first 90 days post-discharge in our TBI sample. Specifically, those aged 66-75 or 76+ had the highest readmission risk over 90 days for both sexes. The findings suggest that clinicians should consider age and sex in discharge planning and for the entire episode of care for the TBI population.

show abstract

“…8,9 There also is mounting clinical and experimental evidence that TBI increases problem alcohol intake. [9][10][11][12] Problem drinking also greatly increases the chances for additional TBI later in life, which can produce much greater impairments in previously injured patients. 4 Children who suffer TBI are less likely to complete their education, find employment, and marry, and are more likely to suffer from poor health, neurological symptoms, and psychiatric ailments, which interact with, or are exacerbated by, alcohol misuse.…”

mentioning

confidence: 99%

Juvenile Traumatic Brain Injury Increases Alcohol Consumption and Reward in Female Mice

Weil

Karelina

Gaier

et al. 2016

Journal of Neurotrauma

Self Cite

View full text Add to dashboard Cite

Traumatic brain injury (TBI) is closely and bi-directionally linked with alcohol use, as by some estimates intoxication is the direct or indirect cause of one-third to one-half of all TBI cases. Alcohol use following injury can reduce the efficacy of rehabilitation and increase the chances for additional injury. Finally, TBI itself may be a risk factor for the development of alcohol use disorders. Children who suffer TBIs have poorer life outcomes and more risk of substance abuse. We used a standardized closed-head injury to model mild traumatic brain injuries. We found that mice injured as juveniles but not during adulthood exhibited much greater alcohol self-administration in adulthood. Further, this phenomenon was limited to female mice. Using behavioral testing, including conditioned place preference assays, we showed that early injuries increase the rewarding properties of alcohol. Environmental enrichment administered after injury reduced axonal degeneration and prevented the increase in drinking behavior. Additionally, brain-derived neurotrophic factor gene expression, which was reduced by TBI, was normalized by environmental enrichment. Together, these results suggest a novel model of alterations in reward circuitry following trauma during development.

show abstract

US Population Estimates of Health and Social Outcomes 5 Years After Rehabilitation for Traumatic Brain Injury

Cited by 171 publications

References 16 publications

Prevalence of suicidal behaviour following traumatic brain injury: Longitudinal follow-up data from the NIDRR Traumatic Brain Injury Model Systems

Prevalence of suicidal behaviour following traumatic brain injury: Longitudinal follow-up data from the NIDRR Traumatic Brain Injury Model Systems

Effects of Age and Sex on Hospital Readmission in Traumatic Brain Injury

Juvenile Traumatic Brain Injury Increases Alcohol Consumption and Reward in Female Mice

Contact Info

Product

Resources

About