Usability of a Digital Registry to Promote Secondary Prevention for Peripheral Artery Disease Patients

Chaudhry, Ahsan; Hankey, Ronald A.; Kaggal, Vinod C.; Bhopalwala, Huzefa; Liedl, David; Wennberg, Paul W.; Rooke, Thom W.; Scott, Christopher G.; Moulder, Magali P. Disdier; Hendricks, Abby K.; Casanegra, Ana I.; McBane, Robert D.; Shellum, Jane L.; Kullo, Iftikhar J.; Nishimura, Rick A.; Chaudhry, Rajeev; Arruda‐Olson, Adelaide M.

doi:10.1016/j.mayocpiqo.2020.09.012

Cited by 3 publications

(1 citation statement)

References 26 publications

(38 reference statements)

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“…Inefficient treatment of PAD patients can contribute to high preventable cardiovascular morbidity and mortality. Accordingly, solutions to improve the rate of optimal management for PAD patients and in-crease their adherence to the treatment are sought for [12][13][14]. The complexity of the situation lies in the fact that observing patients with PAD requires solving multiple problems: first, indications for and type of revascularizing interventions, and second, regardless of the need for revascularization, medication therapy and secondary prevention measures required to prevent the progression of the lower extremities arterial lesions.…”

Section: Onlinementioning

confidence: 99%

Outpatient management of patients with peripheral artery disease by cardiologists or surgeons: influence on the prognosis and prevalence of surgical interventions

Sumin

Medvedeva

Щеглова

et al. 2023

Kompleks. probl. serdečno-sosud. zabol.

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Highlights. The study shows for the first time that during the three-year follow-up of patients with diseases of the arteries of the lower extremities in the observation groups of a general surgeon and a cardiologist, adverse events (myocardial infarction, stroke, amputation, disability) and deaths occurred more often in a surgeon than a cardiologist. The study proves the correctness and real benefit of such an approach with the involvement of a cardiologist to the outpatient stage of management of a complex cohort of patients with atherosclerosis of the vessels of the lower extremities.Aim. To study the effect the outpatient observation of patients with peripheral arteries disease (PAD) by cardiologists and surgeons has on timing and prevalence of reconstructive surgery and the prognosis of patients. Methods We analyzed the data on 585 PAD patients who underwent outpatient observation from 2010 to 2017, dividing them into 2 groups. The first group (131 patients) managed by an surgeon; the second (454 patients) managed by a cardiologist. Since the groups were not comparable in terms of the initial parameters, the comparability of patients in the groups (observation by a surgeon or by a cardiologist) was achieved using pseudorandomization. The follow-up period was three years; we assessed the incidence of deaths, adverse events, and the prevalence of reconstructive operations.Results. During a three-year follow-up the 1st group, compared with the 2nd, had more deaths in general (p<0.001), death from cardiac causes (p = 0.045), from stroke (p><0.001), as well as the total number of adverse events (p><0.001) and disability (p = 0.065). Indications for reconstructive surgery on the lower extremities arteries (LEA), and operations frequency were comparatible in groups. Amputation history, taking diuretics, presence of rhythm disturbances, and management by a surgeon increased the risk of adverse outcomes. Management by a cardiologist, reconstructive LEA surgeries, female sex improved the prognosis of patients. Conclusion Observation of PAD patients by a cardiologist contributes to a higher frequency of optimal drug therapy by patients and can reduce the number of adverse events in patients and improve their survival without affecting the timing and frequency of reconstructive LEA surgeries. Keywords Peripheral atherosclerosis • Outpatient follow-up • Optimal drug therapy • Reconstructive surgery>˂ 0.001), death from cardiac causes (p = 0.045), from stroke (p˂ 0.001), as well as the total number of adverse events (p˂ 0.001) and disability (p = 0.065). Indications for reconstructive surgery on the lower extremities arteries (LEA), and operations frequency were comparatible in groups. Amputation history, taking diuretics, presence of rhythm disturbances, and management by a surgeon increased the risk of adverse outcomes. Management by a cardiologist, reconstructive LEA surgeries, female sex improved the prognosis of patients.Conclusion. Observation of PAD patients by a cardiologist contributes to a higher frequency of optimal drug therapy by patients and can reduce the number of adverse events in patients and improve their survival without affecting the timing and frequency of reconstructive LEA surgeries.

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Section: Onlinementioning

confidence: 99%

Outpatient management of patients with peripheral artery disease by cardiologists or surgeons: influence on the prognosis and prevalence of surgical interventions

Sumin

Medvedeva

Щеглова

et al. 2023

Kompleks. probl. serdečno-sosud. zabol.

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Design, development and evaluation of registry software for upper limb disabilities

Moulaei,

Sheikhtaheri,

Haghdoost

et al. 2024

Healthcare Tech Letters

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Upper limb disabilities, if not managed, controlled and treated, significantly affect the physical and mental condition, daily activities and quality of life. Registries can help control and manage and even treat these disabilities by collecting clinical‐management data of upper limb disabilities. Therefore, the aim of this study is to design, develop and evaluate a registry system for upper limb disabilities in terms of usability. By having identified data elements in the exploratory phase, we developed our registry software using hypertext preprocessor (PHP) programming language in XAMPP software, version 8.1.10. The content and interface validity of the pre‐final version were assessed by 13 experts in the field of medical informatics and health information management. The registry has capabilities to create user profiles, record patient history, clinical records, independence in daily activities, mental health, and treatment processes. It can also generate statistical reports. Participants evaluated the registry's usability as “good” across different dimensions. The registry can help understand upper limb disabilities, improve care, reduce costs and errors, determine incidence and prevalence, evaluate prevention and treatment, and support research and policymaking. The registry can serve as a model for designing registries for other body disabilities.

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Sociotechnical feasibility of natural language processing-driven tools in clinical trial eligibility prescreening for Alzheimer’s disease and related dementias

Idnay,

Liu,

Fang

et al. 2024

Journal of the American Medical Informatics Association

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Background Alzheimer’s disease and related dementias (ADRD) affect over 55 million globally. Current clinical trials suffer from low recruitment rates, a challenge potentially addressable via natural language processing (NLP) technologies for researchers to effectively identify eligible clinical trial participants. Objective This study investigates the sociotechnical feasibility of NLP-driven tools for ADRD research prescreening and analyzes the tools’ cognitive complexity's effect on usability to identify cognitive support strategies. Methods A randomized experiment was conducted with 60 clinical research staff using three prescreening tools (Criteria2Query, Informatics for Integrating Biology and the Bedside [i2b2], and Leaf). Cognitive task analysis was employed to analyze the usability of each tool using the Health Information Technology Usability Evaluation Scale. Data analysis involved calculating descriptive statistics, interrater agreement via intraclass correlation coefficient, cognitive complexity, and Generalized Estimating Equations models. Results Leaf scored highest for usability followed by Criteria2Query and i2b2. Cognitive complexity was found to be affected by age, computer literacy, and number of criteria, but was not significantly associated with usability. Discussion Adopting NLP for ADRD prescreening demands careful task delegation, comprehensive training, precise translation of eligibility criteria, and increased research accessibility. The study highlights the relevance of these factors in enhancing NLP-driven tools’ usability and efficacy in clinical research prescreening. Conclusion User-modifiable NLP-driven prescreening tools were favorably received, with system type, evaluation sequence, and user's computer literacy influencing usability more than cognitive complexity. The study emphasizes NLP's potential in improving recruitment for clinical trials, endorsing a mixed-methods approach for future system evaluation and enhancements.

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Usability of a Digital Registry to Promote Secondary Prevention for Peripheral Artery Disease Patients

Cited by 3 publications

References 26 publications

Outpatient management of patients with peripheral artery disease by cardiologists or surgeons: influence on the prognosis and prevalence of surgical interventions

Outpatient management of patients with peripheral artery disease by cardiologists or surgeons: influence on the prognosis and prevalence of surgical interventions

Design, development and evaluation of registry software for upper limb disabilities

Sociotechnical feasibility of natural language processing-driven tools in clinical trial eligibility prescreening for Alzheimer’s disease and related dementias

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