Case 1 was a 62-year-old man with a hypovascular mass in the pancreatic head and a history of abdominoperineal resection for rectal cancer 4 years ago. Case 2 was a 70-year-old man with a hypovascular mass in the pancreatic body and a history of laparoscopic left hemicolectomy for colon cancer 3 years ago. In both cases, carcinoembryonic antigen levels were elevated at the time of admission. PET showed strong FDG uptake in both tumors. MRCP showed pancreatic masses without stenosis or obstruction of the main pancreatic duct. Both patients were diagnosed with primary pancreatic cancer by endoscopic ultrasound-guided fine-needle aspiration cytology and underwent pylorus-preserving pancreatoduodenectomy and distal pancreatectomy. Pathological examination showed histological findings similar to those for colorectal cancer, with immunostaining negative for CK7 and positive for CK20 and CDX2, resulting in diagnosis of pancreatic metastasis from colorectal cancer. Case 2 had lymph node metastasis in the pancreatic region. The patient in Case 1 had multiple brain and lung metastases, but is alive 3 years and 9 months after pancreatic resection. The patient in Case 2 is alive 2 years and 5 months after pancreatic resection without recurrence. Surgical resection for pancreatic metastasis from colorectal cancer may be recommended as part of multidisciplinary therapy, if there are no uncontrolled metastases in other organs and complete resection is possible.