Usage of retrovirus vectors for gene transfer into birds

Созданы новые упаковочные клетки F18/pJD, содержащие вирус-помощник на базе трансформационно-дефектного мутанта адаптированного к уткам варианта пражского штамма вируса саркомы Рауса (td daPr-RSV-C), которые продуцируют репликативно-дефектньш ретровирусный вектор с титром IO 6 КОЕ/мл. Делетирование цис-активкых последовательностей-ψ упаковочной области и обращенных повторов Е, фланкирующих src, каптированного варианта ретровируса при создании конструкции вируса-помощника позволило получить пул векторного вируса, свободный от последовательностей вируса-помощникаι

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Usage of retrovirus vectors for gene transfer into birds

Cited by 2 publications

References 51 publications

A new retroviral vector system based on the duck-adapted variant of Pr-RSV-C with the extended host ranger

A new retroviral vector system based on the duck-adapted variant of Pr-RSV-C with the extended host ranger

New packaging cells based on the: adapted variant of the Rous sarcoma virus

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