Usage of Silicon for Label-Free Super-Resolved Imaging

Pinhas, Hadar; Danan, Yossef; Meiri, Amihai; Wagner, Omer; Shahmoon, Asaf; Ilovitsh, Tali; Ramon, Yehonatan; Malka, Dror; Danino, Meir; Sinvani, M.; Zalevsky, Zeev

doi:10.1007/978-3-030-21722-8_9

Cited by 1 publication

(1 citation statement)

References 42 publications

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“…Further development of our approach while using timetunable pulses for the pump and the probe allowed us to play with the position of the focus of the probe beam and control its focusing and defocusing processes in deeper layers of the silicon chip [521][522][523][524][525][526] and not only on the wafer's surface. We used probe near IR (at 𝜆 = 1.55 μm) beam and a pump beam at 𝜆 = 775nm with 30 ps pulse width, with a donut shape (generated via beam shaping vortex phase plate).…”

Section: The Conceptmentioning

confidence: 99%

Roadmap on Label‐Free Super‐Resolution Imaging

Astratov,

Sahel,

Eldar

et al. 2023

Laser & Photonics Reviews

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Label‐free super‐resolution (LFSR) imaging relies on light‐scattering processes in nanoscale objects without a need for fluorescent (FL) staining required in super‐resolved FL microscopy. The objectives of this Roadmap are to present a comprehensive vision of the developments, the state‐of‐the‐art in this field, and to discuss the resolution boundaries and hurdles that need to be overcome to break the classical diffraction limit of the label‐free imaging. The scope of this Roadmap spans from the advanced interference detection techniques, where the diffraction‐limited lateral resolution is combined with unsurpassed axial and temporal resolution, to techniques with true lateral super‐resolution capability that are based on understanding resolution as an information science problem, on using novel structured illumination, near‐field scanning, and nonlinear optics approaches, and on designing superlenses based on nanoplasmonics, metamaterials, transformation optics, and microsphere‐assisted approaches. To this end, this Roadmap brings under the same umbrella researchers from the physics and biomedical optics communities in which such studies have often been developing separately. The ultimate intent of this paper is to create a vision for the current and future developments of LFSR imaging based on its physical mechanisms and to create a great opening for the series of articles in this field.

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