2006
DOI: 10.1542/peds.2006-0416
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Use and Efficacy of Endotracheal Versus Intravenous Epinephrine During Neonatal Cardiopulmonary Resuscitation in the Delivery Room

Abstract: Endotracheal epinephrine is frequently used when intensive resuscitation is required in the delivery room. The previously recommended endotracheal epinephrine dose of 0.01 to 0.03 mg/kg is often ineffective. Higher endotracheal doses will likely be needed to improve efficacy. A prospective study is needed to determine the best endotracheal epinephrine dosing regimen. Until such information is available, intravenous administration should be the preferred route of delivery.

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Cited by 229 publications
(146 citation statements)
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“…[1][2][3] Although the vast majority of newborn infants do not require intervention to make these transitional changes, the large number of births worldwide means that many infants require some assistance to achieve cardiorespiratory stability each year.…”
Section: Newborn Transitionmentioning
confidence: 99%
“…[1][2][3] Although the vast majority of newborn infants do not require intervention to make these transitional changes, the large number of births worldwide means that many infants require some assistance to achieve cardiorespiratory stability each year.…”
Section: Newborn Transitionmentioning
confidence: 99%
“…[1][2][3] Infants who require resuscitation at birth (have depressed breathing, activity, and/or require supplemental oxygen) are recommended to be transferred to an environment where close monitoring and anticipatory care can be provided once adequate ventilation and circulation have been established. 4,5 There is no clear distinction in the Neonatal Resuscitation Program (NRP) guidelines between those who receive short period of positive pressure ventilation (PPV) at birth and those who require prolonged and more extensive resuscitation in terms of the postresuscitation care (PRC) needed.…”
mentioning
confidence: 99%
“…About 90% of newborns cry immediately after delivery; have vigorous activity and suffer no complication [30]. About 5 to 10% require some measure of assistance to establish spontaneous respiration while about 1% needs extensive resuscitation at birth [30].…”
Section: Newborn and Other Postnatal Caresmentioning
confidence: 99%
“…About 5 to 10% require some measure of assistance to establish spontaneous respiration while about 1% needs extensive resuscitation at birth [30]. The need to assist the newborn is most often assessed using the Apgar score which is assessed at birth and again at the fifth minute of life, however other methods are available.…”
Section: Newborn and Other Postnatal Caresmentioning
confidence: 99%