“…Of the included 92 papers, 38% (35 paper) reported the integration of VS in surgical training for medical undergraduates, among which 12 studies focused on the instructional application of virtual endoscopic [including laparoscopic ( 31 , 36 , 37 , 56 , 73 , 76 , 78 , 98 ), arthroscopic ( 26 , 47 , 48 ), and otoscopic ( 53 )] simulators; 7 studies were for learning procedures or concepts of orthopedic and bone surgery ( 32 , 33 , 35 , 45 , 57 , 66 , 70 ); 5 studies were based on VS system or platform as a primary mode of teaching neurosurgical procedures, neuroanatomy and pathologies ( 22 , 28 , 71 , 80 , 81 ); 4 papers ( 38 , 61 , 75 , 84 ) reported the exposure of medical undergraduates as novice surgeons to the robotic surgery simulators; 2 studies conducted by the same team ( 64 , 65 ) explored the VR simulation-based training in Cochlear Implant surgery; the other 2 were for learning basic motor skills in liver surgery ( 50 , 52 ); 1 in minimally invasive surgery ( 97 ), and 1 in vitreoretinal surgery ( 67 ). In addition, Fukuta et al ( 46 ) generated a virtual operating theater orientation to improve knowledge and confidence of medical undergraduates. Except five validation studies of virtual simulators ( 26 , 47 , 53 , 65 , 81 ) in which the undergraduates acted as the novice group for comparison with the skilled group, the findings of all the other included studies positively supported the usability and its feasibility of integrating VS in surgical training.…”