Use of a conventional mass spectrometer as a detector for gas chromatography

Lindeman, L. P.; Annis, J. L.

doi:10.1021/ac50153a011

Cited by 77 publications

(16 citation statements)

References 12 publications

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“…In the next decade, many scientists in many laboratories realized the great potential of GC/MS [29][30][31][32][33][34]. Especially critical for its development were methods for GC carrier gas removal, such as effusion separators (Watson-Biemann), jet separators (Ryhage-Stenhagen), and semipermeable membranes (UeweUyn-Littlejohn).…”

Section: Further Gas Chromatography/mass Spectrometry Developmentmentioning

confidence: 99%

Early gas chromatography/mass spectrometry

Gohlke

McLafferty

1993

J. Am. Soc. Mass Spectrom.

147

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Spectroscopy Laboratory, The Dow Chemical Company, Midland, Michigan, USA In December 1955 or thereabouts, the authors coupled a homemade gas chromatograph to a research time-of-flight mass spectrometer constructed by W. C. Wiley, I. H. McLaren, and D. B. Harrington. This unique gas chromatography/mass spectrometry (GC/MS) instrument generated mass spectra at a lo-kHz rate for display on an oscilloscope; eluted gas chromate graphic components, such as methanol, acetone, benzene, toluene, and carbon tetrachloride, could be visually identified immediately from the oscilloscope display. Many years of further research and development in many laboratories worldwide were necessary, however, to make continuous on-line GC/MS the uniquely valuable analytical tool that it is today.

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Section: Further Gas Chromatography/mass Spectrometry Developmentmentioning

confidence: 99%

Early gas chromatography/mass spectrometry

Gohlke

McLafferty

1993

J. Am. Soc. Mass Spectrom.

147

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“…In conclusion, it is appropriate to note that this technique is only an extension of work pioneered and established by other workers (Ebert, 1961 ;Gbhlke, 1959;Lindeman and Annis, 1960). Because it makes possible separations and mass analysis not attained from previously described techniques, it is desirable to emphasize the simplicity with which capillary chromatography can be coupled to a rapid-scan mass spectrometer.…”

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confidence: 95%

“…In recent years considerable attention has been given to the direct introduction into a rapid-scan mass spectrometer of effluents emerging from a gas chromatographic column (Ebert, 1961;Gohlke, 1959 ;Lindeman and Annis, 1960). This technique is of value when it is not possible or convenient to collect the effluent and perform the analysis bj means of a conventional inlet system, for example, when the unknown chemical is unstable and polymerizes or oxidizes before the operator can perform the mass analysis.…”

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confidence: 99%

Use of Capillary Gas Chromatography with a Time‐of‐Flight Mass Spectrometer

McFadden

Teranishi

Black

et al. 1963

Journal of Food Science

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SUMMARY The feasibility and advantages of using a capillary chromatographic column directly with a time‐of‐flight mass spectrometer were demonstrated in the analysis of several flavor extracts. The high resolving power of this column proved to be indispensable in cases where chromatographic fractions previously unresolved showed similar mass spectra. Other limitations of this combined technique are covered.

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“…Some important applications to geochemical problems are illustrated by the separation on a capillary column of saturated hydrocarbons up to C l l and their mass spectrometric identification [90]. The same group analyzed olefinic compounds [91] and hydrocarbons in the C s to C 9 range.…”

Section: F Gas Chromatograph-mass Spectrometer Couplingmentioning

confidence: 99%