Use of a novel smartphone-based application tool for enrolment and randomisation in pre-hospital clinical trials

Randomised trial of the clinical and cost effectiveness of a supraglottic airway device compared with tracheal intubation for in-hospital cardiac arrest (AIRWAYS-3): Protocol, design and implementation

“…To our knowledge, only one other published paper has described the use of a smartphone-based application tool for randomisation. 35 It has considerable advantages over the use of sealed opaque envelopes or telephone/computer-based randomisation systems in terms of availability, speed and vulnerability to tampering, and could be applied to future clinical trials requiring a reliable time-sensitive randomisation procedure.…”

Defibrillation trials: POSED a challenge

“…At least two other resuscitation trials have also adopted the use of mobile phone and computer applications to aid in the recruitment, randomisation and follow-up of patients in both the prehospital and in-hospital environments. 17 , 18 These applications are also capable of facilitating the notification of enrolments to the trial team in real-time, 18 potentially minimising delays in data collection and patient consent.…”

Resuscitation Plus Special Issue: Cardiac arrest research

“… 8 , 9 , 10 , 11 In response to this challenge, researchers in collaboration with frontline clinicians have developed novel smartphone randomisation that might facilitate rapid individual patient randomisation in the pre-hospital cardiac arrest setting. 12 …”