Use of a synthetic dural substitute to prevent ventral retethering in the management of diastematomyelia

Shivapathasundram, Ganeshwaran; Stoodley, Marcus A.

doi:10.1016/j.jocn.2011.08.018

Cited by 7 publications

(2 citation statements)

References 31 publications

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“…These risks of complications necessitate duraplasty during decompressive craniotomy. Accumulating data have shown that tension-reduced duraplasty with artificial dura mater material can effectively reduce leakage of cerebrospinal fluid and occurrence of secondary seizure [ 15 – 18 ]. Our data demonstrate that synthetic medical glue has a great advantage in tension-reduced duraplasty, with satisfactory results but minimal complications.…”

Section: Discussionmentioning

confidence: 99%

Application of COMPONT Medical Adhesive Glue for Tension-Reduced Duraplasty in Decompressive Craniotomy

et al. 2016

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BackgroundThe aim of this study was to evaluate the application of medical adhesive glue for tension-reduced duraplasty in decompressive craniotomy.Material/MethodsA total of 56 cases were enrolled for this study from Jan 2013 to May 2015. All patients underwent decompressive craniotomy and the dura was repaired in all of them with tension-reduced duraplasty using the COMPONT medical adhesive to glue artificial dura together. The postoperative complications and the healing of dura mater were observed and recorded.ResultsNo wound infection, epidural or subdural hematoma, cerebrospinal fluid leakage, or other complications associated with the procedure occurred, and there were no allergic reactions to the COMPONT medical adhesive glue. The second-phase surgery of cranioplasty was performed at 3 to 6 months after the decompressive craniotomy in 32 out of the 56 cases. During the cranioplasty we observed no adherence of the artificial dura mater patch to the skin flap, no residual COMPONT glue, or hydropic or contracture change of tissue at the surgical sites. Additionally, no defect or weakening of the adherence between the artificial dura mater patch and the self dura matter occurred.ConclusionsCOMPONT medical adhesive glue is a safe and reliable tool for tension-reduced duraplasty in decompressive craniotomy.

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Section: Discussionmentioning

confidence: 99%

Application of COMPONT Medical Adhesive Glue for Tension-Reduced Duraplasty in Decompressive Craniotomy

et al. 2016

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“…Other materials have been used as dural substitutes include synthetic polymers, such as ploy‐lactic acid (PLA), poly‐ɛ‐caprolactone (PCL), expanded polytetrafluoroethylene, polyurethane, polyethylene glycol hydrogels, and hydroxyethylmethacrylate hydrogels, and natural polymers, such as collagen, gelatin, fibrinogen, and alginate hydrogels. Some of these materials have been commercially available and have gained widespread use as onlay materials (e.g., GORE PRECLUDE ® MVP ® , DuraPatch ® , DuraMatrix‐Onlay™, and Gelfoam ® ) .…”

Section: Introductionmentioning

confidence: 99%

Multilayer scaffold of electrospun PLA–PCL–collagen nanofibers as a dural substitute

2013

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Dural closure after the neurosurgery can prevent postoperative complications. Although many types of dural substitute have been developed, most of them lack functional and structural characteristics compared with the natural dura mater. In this study, we used electrospinning method to fabricate a multilayer scaffold to promote dural repair. The inner layer of the scaffold that faces the brain tissue is composed of poly-lactic acid (PLA) to reduce tissue adhesion. The middle layer of the scaffold is composed of poly-ɛ-caprolactone and PLA, which provides a watertight seal. The outer layer of the scaffold contains a large amount of collagen to promote cell attachment and proliferation. The results from in vitro study and an animal model have shown that this multilayer fibrous scaffold has sufficient mechanic strength and biochemical properties to enhance dural repair. Therefore, fabrication of scaffold with multiple functional and structural layers may provide a novel approach for tissue engineering.

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Split Cord Malformations

Kurdi

2024

Congenital Spine Malformations

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Use of a synthetic dural substitute to prevent ventral retethering in the management of diastematomyelia

Cited by 7 publications

References 31 publications

Application of COMPONT Medical Adhesive Glue for Tension-Reduced Duraplasty in Decompressive Craniotomy

Application of COMPONT Medical Adhesive Glue for Tension-Reduced Duraplasty in Decompressive Craniotomy

Multilayer scaffold of electrospun PLA–PCL–collagen nanofibers as a dural substitute

Split Cord Malformations

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