Use of Air to Decrease Endothelial Cell Loss During Intraocular Lens Implantation

Bourne, William M.; Brubaker, Richard F.; O’Fallon, W. Michael

doi:10.1001/archopht.1979.01020020135009

Cited by 82 publications

(18 citation statements)

References 16 publications

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“…Contact between the lens and the endothelium is one important factor . The use of an air interface between the cornea and the lens during the operation has been shown to reduce the cell loss (Bourne et al 1979). The duration of the operation is longer with lens implantation, and during that time the endothelium is deprived a normal nutritive supply from the aqueous humour.…”

mentioning

confidence: 38%

Corneal Thickness and Endothelial Damage After Intraocular Lens Implantation

Olsen

Eriksen

1980

Acta Ophthalmologica

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The corneal thickness and the specular appearance of the corneal endothelium are reported in 100 patients with unilateral intraocular lens implantation. Post-operative time ranged from one to 42 months. An average central endothelial cell loss of uncomplicated cases of 46%, range 1 to 83%, with no correlation with time after the operation was found. A significantly higher cell loss was found in cases with technical complications, shallow anterior chamber or increased intraocular pressure post-operatively. No correlation was found between the corneal thickness and the endothelial cell loss. In two patients, however, with a cell density below 500 cells/mm2, a slight increase in corneal thickness was noted. Thirty patients presented a guttate endothelium. Irrespective of the occurrence of surgical complications the presence of a guttate endothelium was found to be a major determinant of the corneal thickness increase and could be ascribed as a cause of persistent corneal swelling in six of twelve patients with elevated corneal thickness. The progression of guttate changes occurred independently of the cell loss.

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mentioning

confidence: 38%

Corneal Thickness and Endothelial Damage After Intraocular Lens Implantation

Olsen

Eriksen

1980

Acta Ophthalmologica

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“…The implantation of an intraocular lens (IOL) significantly increases the loss of corneal endothelial cells during cataract surgery (Bourne 8c Kaufman 1976): Introduction of 'deep-chamber techniques' and development of new IOL-styles led to a reduction of the average cell loss to about 6%--20% (Binkhorst et a1 1978: Bourne et al 1979: Bourne et al 1981). Nevertheless, recent studies (Kraff et al 1982: Drews 1982Tavlor et al 1983: Waring et al 1983) still cautioned of the occurrence of bullous keratopathy after IOL implantation.…”

supporting

confidence: 42%

Changes of the Corneal Endothelium Following Intracapsular Cataract Extraction With Implantation of Semiflexible Anterior Chamber Lenses

Stur

Grabner

Dorda

1984

Acta Ophthalmologica

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A consecutive group of 103 patients with senile cataract underwent intracapsular cataract extraction and implantation of a semiflexible anterior chamber lens. After 6 month of follow-up, there was an average decrease of 20% +/- 15% in central corneal endothelial cell density and an average vertical disparity of 32% +/- 20% between central and superior endothelial areas. The endothelial cell loss was not correlated with pre-operative cell density. There was a positive correlation between age and cell loss and between age and vertical disparity. Findings in eyes with cornea guttata did not differ significantly from those without guttata. Anterior vitrectomy did not increase endothelial cell loss significantly. Maintenance of a deep anterior chamber by pre-operative oculopression or by instillation of Na-hyaluranate had no significantly different effect on the corneal endothelial cell loss.

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“…At 1-5 days after cataract extraction, a variable decrease in endothelial cell density was noted depending upon surgical trauma. 45 After these initial cell losses, the endothelial cell density decreases at an average rate of 2.5% per year for at least 10 years after surgery, with or without a lens implant. 46 This is four times the rate in unoperated eyes.…”

Section: Secondary Corneal Endotheliopathiesmentioning

confidence: 99%