Use of an empty, plasmapore-covered titanium cage for interbody fusion after anterior cervical microdiscectomy

Krayenbühl, Niklaus; Schneider, Christian A.; Landolt, Hans; Fandiño, Javier

doi:10.1016/j.jocn.2006.12.011

Cited by 14 publications

(8 citation statements)

References 48 publications

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“…Stand‐alone plasma‐sprayed Ti implants without additional bone graft material (Fig. ) have been used in cervical and lumbar fusion, successful fusion having been assessed indirectly by absence of segmental motion on dynamic X‐rays and by presence of bone bridges surrounding the cages.…”

Section: Surface Modification Of Ti and Its Alloysmentioning

confidence: 99%

Spine Interbody Implants: Material Selection and Modification, Functionalization and Bioactivation of Surfaces to Improve Osseointegration

Rao

Pelletier

Walsh

et al. 2014

Orthopaedic Surgery

227

177

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The clinical outcome of lumbar spinal fusion is correlated with achievement of bony fusion. Improving interbody implant bone on-growth and in-growth may enhance fusion, limiting pseudoarthrosis, stress shielding, subsidence and implant failure. Polyetheretherketone (PEEK) and titanium (Ti) are commonly selected for interbody spacer construction. Although these materials have desirable biocompatibility and mechanical properties, they require further modification to support osseointegration. Reports of extensive research on this topic are available in biomaterial-centric published reports; however, there are few clinical studies concerning surface modification of interbody spinal implants. The current article focuses on surface modifications aimed at fostering osseointegration from a clinician's point of view. Surface modification of Ti by creating rougher surfaces, modifying its surface topography (macro and nano), physical and chemical treatment and creating a porous material with high interconnectivity can improve its osseointegrative potential and bioactivity. Coating the surface with osteoconductive materials like hydroxyapatite (HA) can improve osseointegration. Because PEEK spacers are relatively inert, creating a composite by adding Ti or osteoconductive materials like HA can improve osseointegration. In addition, PEEK may be coated with Ti, effectively bio-activating the coating.

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Section: Surface Modification Of Ti and Its Alloysmentioning

confidence: 99%

Spine Interbody Implants: Material Selection and Modification, Functionalization and Bioactivation of Surfaces to Improve Osseointegration

Rao

Pelletier

Walsh

et al. 2014

Orthopaedic Surgery

227

177

View full text Add to dashboard Cite

show abstract

“…Many authors have suggested that ACDF-CA can provide immediate stability, increased disc and foraminal height, and solid fusion with few complications3,9,11,19,21). Cages, which have good structural strength, are made up of biocompatible materials such as Carbon, polyetheretherketone, and Titanium.…”

Section: Introductionmentioning

confidence: 99%

Radiographic Comparison of Four Anterior Fusion Methods in Two Level Cervical Disc Diseases : Autograft Plate Fixation versus Cage Plate Fixation versus Stand-Alone Cage Fusion versus Corpectomy and Plate Fixation

Kim

Jeon

et al. 2012

J Korean Neurosurg Soc

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ObjectiveTo evaluate radiographic results of anterior fusion methods in two-level cervical disc disease : tricortical autograft and plate fixation (ACDF-AP), cage and plate fixation (ACDF-CP), stand-alone cage (ACDF-CA), and corpectomy and plate fixation (ACCF).MethodsThe numbers of patients were 70 with a minimum 6 month follow-up (ACDF-AP : 12, ACDF-CP : 27, ACDF-CA : 15, and ACCF : 16). Dynamic simple X-ray and computed tomography were evaluated preoperatively, postoperatively, 6 month, and at the final follow-up. The fusion and subsidence rates at the final were determined, and global cervical lordosis (GCL), cervical range of motion, fused segment angle (FSA), and fused segment height (FSH) were analyzed.ResultsNonunion was observed in 4 (25%) patients with ACDF-CA, 1 (8%) patient with ACDF-AP, 1 (4%) patient with ACDF-CP. The number of loss of FSH (%) more than 3 mm were 2 patients (16%) in ACDF-AP, 3 patients (11%) in ACDF-CP, 5 patients (33%) in ACDF-CA, and 3 patients (20%) in ACCF. The GCL was decreased with ACDF-CA and increased with others. The FSA was increased with ACDF-AP, ACDF-CP, and ACCF, but ACDF-CA was decreased. At the final follow-up, the FSH was slightly decreased in ACDF-CP, ACDF-AP, and ACCF, but ACDF-CA was more decreased. Graft related complication were minimal. Screw loosening, plate fracture, cage subsidence and migration were not identified.ConclusionACDF-CP demonstrated a higher fusion rate and less minimal FSH loss than the other fusions in two-level cervical disc disease. The ACDF-AP and ACCF methods had a better outcome than the ACDF-CA with respect to GCL, FSA, and FSH.

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“…Krayenbuhl et al, in their series of patients affected by cervical myelo-radiculopathies, described a 98% fusion rate with only 2% of subsidence [18]. Arregui et al, implanted Cespace in a series of 104 patients.…”

Section: Discussionmentioning

confidence: 99%

Use of Stand-Alone Intersomatic Titanium Interbody Cage Cespace for Cervical Anterior Arthrodesis and Fusion in Cervical Degenerative Diseases

Cacciola¹,

Ghetti²,

Caruso³

et al. 2021

Preprint

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Background: Cespace is a solid titanium spacer used for arthrodesis and fusion between vertebral cervical bodies in the treatment of degenerative diseases of cervical spine. Methods: We present our clinical experience in a group of 180 patients, affected by cervical myelo-radiculopathy due to spondylosis or cervical disc herniation and undergone surgical operation. All patients underwent an anterior discectomy and interbody fusion through positioning of one or more levels Cespace device. Patients were evaluated by clinical and radiological assessment pre-operatively, immediately post-operatively and at follow-up. We assess clinical outcome using visual analogue scale for pain and a modified Japanese Orthopedic Association scale for myelopathy. We also considered functional outcome, using Odom classification. Results: After surgical treatment we report a significant relief of pain and clinical improvement. Radiological evaluations showed no change in cervical lordosis. No case of junctional syndrome was observed over all follow-up period. Conclusion: Cespace is a safety and efficacious orientated solution for cervical interbody fusion.

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Use of an empty, plasmapore-covered titanium cage for interbody fusion after anterior cervical microdiscectomy

Cited by 14 publications

References 48 publications

Spine Interbody Implants: Material Selection and Modification, Functionalization and Bioactivation of Surfaces to Improve Osseointegration

Spine Interbody Implants: Material Selection and Modification, Functionalization and Bioactivation of Surfaces to Improve Osseointegration

Radiographic Comparison of Four Anterior Fusion Methods in Two Level Cervical Disc Diseases : Autograft Plate Fixation versus Cage Plate Fixation versus Stand-Alone Cage Fusion versus Corpectomy and Plate Fixation

Use of Stand-Alone Intersomatic Titanium Interbody Cage Cespace for Cervical Anterior Arthrodesis and Fusion in Cervical Degenerative Diseases

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