2014
DOI: 10.1007/s11094-014-1106-7
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Use of an F Complex in the Pilot-Scale Production of Z-Phe-D-Trp-Lys(ε-Boc)OH

Abstract: A method for using an F complex for pilot-scale production of Z-Phe-D-Trp-Lys(e-Boc)OH -a protected tripeptide used in making synthetic analogs of somatostatin is described. This method involves regeneration of pentafluorophenol and allows the target compound to be prepared with a main substance content of~99%.

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