Use of An ipsilateral Vascularized Ulnar Transposition Autograft for Limb‐Sparing Surgery of the Distal Radius in Dogs: An Anatomic and Clinical Study

Mison, Michael B.; Steficek, Barbara A.; Lavagnino, Michael; Teunissen, Brian D.; Hauptman, Joe G.; Walshaw, Richard

doi:10.1053/jvet.2003.50003

Cited by 43 publications

(20 citation statements)

References 17 publications

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“…The process of wound healingisdivided into fouro verlapping stages: inflammation, debridement, repair,a nd maturation (20)(21)(22)(23)(24).One of theprimarygoalsofusing misoprostol in this study wastoattenuatethe inflammatory stage of healing by inhibiting IL-1,thromboxane,and TNF-alpha and beta (6,14).Thismay helptominimize thecardinal signso fi nflammation( redness, pain, heat, anddecrease patient discomfort. Subjectively,t he wounds treated with thev ehicle, 'avicel', and misoprostol produced a larger amount of exudated uringt he presumed inflammatory and debridement stages (days 2-7).…”

Section: Discussionmentioning

confidence: 99%

“…Human reports exist describings ignificant plasma misoprostol levels 10 minutes following an oral rinse or vaginal application (22).Localapplicationofmisoprostol to surgicalsites in theoral cavity of dogs demonstrateds timulationo fn ew bone formation and an increased rate of periodontal regeneration; howeverp lasma concentrations of misoprostol were not evaluated (16)(17)(18).I n one report, systemic effects were evaluated by sampling tissues from sites distant to the siteo fa pplication. The expected effects attributable to misoprostol couldo nlyb e found up to 1cmfromthe area of local infusion.Although these studies do not eliminate thepossibility of systemic absorptionoflocally applied misoprostol, theys uggestt hat theb ioavailabilitym ay differ between oral, mucosal, and wound applications.…”

Section: Discussionmentioning

confidence: 99%

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An investigation of misoprostol in the promotion of wound healing

Vandervoort¹,

Nieves²,

Fales-Williams³

et al. 2006

Vet Comp Orthop Traumatol

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Misoprostol is a synthetic analogue of prostaglandin E1 that is known to attenuate the inflammatory process and promote collagen formation by inhibiting IL-1 and TNF. The objective of this study was to determine if the application of misoprostol wound powder to open wounds in dogs would modulate inflammation and decrease wound healing time. This prospective randomized study included 20 dogs with 281 surgically created 8 mm open wounds over the dorsum. The wounds were assigned to one of three treatments: control (no treatment), treatment (misoprostol powder with 'avicel'), or vehicle ('avicel' alone). Open wounds were digitally photographed on days zero, one, three, seven, 10, and 15 to measure wound size. All wounds were harvested at day 15 and evaluated histologically for evidence of edema, inflammation, necrosis, and collagen characteristics. Amount of epithelialization of open wounds was not significantly different among the groups at days three, seven, 10, and 15. The vehicle treated wounds were found to have a significantly higher degree of necrosis in comparison to control and treatment wounds. The control wounds had significantly lower scores for deep inflammation. All of the other parameters evaluated including location of wound, oedema, and characteristics of collagen fibres in the wound showed no significance among groups. However, the total wound score for the misoprostol was statistically higher than that for the control wounds. Therefore the value of using misoprostol wound powder with 'avicel' as the vehicle to enhance wound healing cannot be substantiated by the results of this study.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

An investigation of misoprostol in the promotion of wound healing

Vandervoort¹,

Nieves²,

Fales-Williams³

et al. 2006

Vet Comp Orthop Traumatol

View full text Add to dashboard Cite

show abstract

“…Other applications include the sealing and removal of hollow organ structures <9mm in diameter in general urologic, thoracic, plastic and reconstructive procedures. 25 …”

Section: Hemostasismentioning

confidence: 99%

Update on Surgical Principles and Equipment

Kroner

Budgeon

Colopy

2016

Veterinary Clinics of North America: Exotic Animal Practice

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“…Laser surgery is an attractive alternative to other means of section device in terms of tissue inflammation and interaction [1], which has been extensively used in human [2-5] and veterinary medicine [6-8]. …”

Section: Introductionmentioning

confidence: 99%

Fire ignition during laser surgery in pet rodents

Collarile¹,

Girolamo²,

Nardini³

et al. 2012

BMC Vet Res

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BackgroundLaser surgery is an attractive alternative to other means of section device in terms of tissue inflammation and interaction, which has been extensively used in human and veterinary medicine. Although accidental ignition during laser surgeries is sporadically reported in human medical literature, to the authors’ knowledge this is the first report regarding laser-dependent fire ignition during surgery in veterinary medicine.Case presentationTwo rodents, a 13-month old, 27-gram, male pet mouse (Mus musculus) and a 1-year old, female Russian hamster (Phodopus sungorus), underwent surgical removal of masses with diode laser. During the surgical procedures fires ignited from the face masks. The mouse presented severe burns on the head and both forelimbs, it was hospitalized and approximately 2 months after surgery burns were resolved. The hamster presented severe burns on the face and the proximal regions of the body. At 72 hours from the accident the hamster was euthanized.ConclusionThe present report suggests that fire ignition is a potential life-threatening complication of laser surgery in non-intubated rodents maintained under volatile anesthesia. High oxygen concentrations, the presence of combustible, and the narrowness of the surgical field with the face mask during laser surgery on rodents are risk factors for fire ignition.

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Use of An ipsilateral Vascularized Ulnar Transposition Autograft for Limb‐Sparing Surgery of the Distal Radius in Dogs: An Anatomic and Clinical Study

Cited by 43 publications

References 17 publications

An investigation of misoprostol in the promotion of wound healing

An investigation of misoprostol in the promotion of wound healing

Update on Surgical Principles and Equipment

Fire ignition during laser surgery in pet rodents

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