Use of assisted reproductive technology to separate sperm from human immunodeficiency virus infected men resulting in pregnancy among serodiscordant couples

Abstract

Due to HIV care improvement, discordant couples more frequently seek help in order to conceive their own biological child. Besides the advance of antiretroviral therapy, unprotected intercourse is not a complete safe option, carrying a low but still present risk of HIV transmission. We report 10 serodiscordant couples in whom the male partner is HIV positive, submitted to sperm washing and intrauterine insemination. The procedure resulted in four pregnancies and no HIV transmission to mother or child was observed. Techniques of assisted reproduction can help HIV discordant couples to conceive biological offspring and is a safer option than unprotected intercourse.

Outcome of Intra Uterine Insemination for HIV Serodiscordant Couple

“…Thus, couples of reproductive age in which the man is HIV-1 infected and who wish to have a child with their own gametes can only resort to medically assisted procreation (MAP) because unprotected intercourse at the time of ovulation goes against prevention campaigns [3]. HIV serodiscordant couple who wish to have offspring but fear of disease contagious prohibited them from concieved naturally [4]. Intrauterine insemination without having direct sexual contact is one of the method to achieve this wish [5].…”