Use of axial length to estimate the vitreous chamber volume in pseudophakic

Santana, Juliana Moreira de; Cordeiro, Gabriel Guerra; Soares, Daniel Tenório Camelo; Costa, Marília Rocha; Pinto, Alexandre Paashaus da Costa; Lira, Rodrigo Pessoa Cavalcanti

doi:10.1007/s00417-020-04991-3

Cited by 7 publications

(5 citation statements)

References 11 publications

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“…However, in practice, the volume of vitreous can vary between individuals, which is believed to affect vitrectomy time. Some studies, using methods such as computed tomography or measuring the volume of the fluid filling the vitreous cavity after vitrectomy, have reported a significant correlation between axial length and vitreous volume [20][21][22]. Therefore, in this study, cases with excessively short or long axial length were excluded, and no significant correlation was found between axial length and vitrectomy time in any of the four groups.…”

Section: Discussionmentioning

confidence: 88%

Clinical Performance Comparison of Ultrahigh-speed Dual Pneumatic Vitrectomy Probes: Is Faster and Smaller Better?

Lee,

Choi

2024

Korean J Ophthalmol

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Purpose: Various vitrectomy probes are currently being used commercially, and there are ongoing efforts toward developing probes with higher cutting rates and smaller gauges. This study aimed to compare the efficiency and safety of various commercially available small gauge ultrahigh-speed dual pneumatic vitrectomy probes.Methods: We retrospectively analyzed the medical records of patients and recorded intraoperative videos while they underwent microincision three-port vitrectomy surgery for idiopathic epiretinal membrane at Soonchunhyang University Seoul Hospital. The patients were categorized into four groups based on the vitrectomy probe used during surgery: 23-7500 (UltraVit 23-gauge 7,500 cuts per minute [CPM]), 23-7500 (UltraVit 25-gauge 7,500 CPM), 25-10K (Advanced UltraVit 25-gauge 10,000 CPM), and 27-10K (Advanced UltraVit 27-gauge 10,000 CPM).Results: In total, 82 eyes from 82 patients were included in this work, with 16, 11, 26, and 29 eyes in groups 23-7500, 25-7500, 25-10K, and 27-10K, respectively. The corresponding vitrectomy times were 295.56 ± 53.55, 293.09 ± 50.28, 299.92 ± 59.42, and 349.38 ± 67.23 seconds, respectively. There was a significant difference in the vitrectomy time between the groups (<i>p</i> = 0.004). The mean number of sutures was 3, 3, 2.96, and 0.83, respectively. In the 23-7500 group, there was one case of iatrogenic retinal break, while in the 27-10K group, there was one case of postoperative hypotony.Conclusions: Although advancements have been made in the 27-gauge vitrectomy probe, it still takes more vitrectomy time than it does when using the 23- and 25-gauge probes. However, the delay was within an average of 1 minute, and considering the significantly reduced need for sutures, there is a substantial benefit in terms of postoperative discomfort. Therefore, when choosing a probe for epiretinal membrane surgery among the four options, it is reasonable to select the 27-gauge probe according to the surgeon’s preference.

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Section: Discussionmentioning

confidence: 88%

Clinical Performance Comparison of Ultrahigh-speed Dual Pneumatic Vitrectomy Probes: Is Faster and Smaller Better?

Lee,

Choi

2024

Korean J Ophthalmol

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“…One study investigated in patients that underwent vitrectomy surgery for a macular hole or an epiretinal membrane showed that the vitreous chamber volume was significantly correlated with the axial length and that the former could probably be calculated using biometry [ 14 ]. The authors stated that the vitreous chamber had a very variable volume.…”

Section: Discussionmentioning

confidence: 99%

VIVEX: A Formula for Calculating Individual Vitreous Volume: A New Approach Towards Tailored Patient Dosing Regime in Intravitreal Therapy

Borkenstein,

Langenbucher

2023

Ophthalmol Ther

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Introduction Personalized medicine and patient-tailored drug dosing have been substantiated through thousands of clinical studies, demonstrating their safety and efficacy. The principle: “as much as necessary, as little as possible” is widely spread. Quantities and doses are therefore adjusted individually. This is not the case for intravitreal injections in the context of retinal diseases. Intravitreal injections are not adjusted in relation to the vitreous volume. The vitreous body is described as “approx. 4 cm 3 ” in the literature. Methods In this retrospective observational study, we included 72 eyes of patients who had undergone magnetic resonance imaging (MRI) of the orbit and biometry measurements of the anterior chamber depth (ACD) and axial length. After segmentation of the volume data, the vitreous volume was extracted by voxel integration, and a simple prediction model was derived to determine the vitreous volume from the axial length (AL) measurement with AL 3 ·π/6·(0.76 + 0.012·(AL-24). This is the volume of a sphere AL 3 ·π/6 and a correction term 0.76 + 0.012·(AL-24) to account for the portion of the vitreous in the entire globe and the proportional increase of the vitreous portion for long (myopic) eyes. Results Emmetropic eyes with an axial length of 22.50–23.50 mm had a vitreous volume of around 4.5–5.5 cm 3 . Myopic eyes with an axial length of 30.00 mm had a calculated vitreous volume of 9.0–10.0 cm 3 . Hypermetropic eyes with an axial length of 20.00 mm showed a vitreous volume of 3.0–4.0 cm 3 . Conclusions By implementing the new calculation formula on the IOLCON website, it will be easy to get the exact individual vitreous volume. The data could be used by retinal surgeons prior to surgery. The knowledge of anatomical dimensions and exact individual vitreous volume seems to be important for gas and silicone oil fillings. With the newly derived knowledge, multicentric studies can evaluate the impact of the dose in intravitreal therapies. Patient-tailored dosing could prevent side effects and improve effectiveness.

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“…The AL was used to estimate the volume of the vitreous chamber (6) . The amount of C 3 F 8 injected intravitreally was calculated based on the estimated volume of the vitreous cavity.…”

Section: Thismentioning

confidence: 99%

Influence of the dilution method on the intraocular duration of C3F8 in vitrectomy for macular hole: a randomized clinical trial

Pinto,

Soares,

Costa

et al. 2024

ABO

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To compare the injection of small amounts of undiluted C 3 F 8 with the traditional gas injection in vitrectomy for macular hole treatment. Methods: This clinical trial included 26 individuals divided into two groups. Group 1 received an intravitreal injection of 0.9-1.0 mL of 100% C 3 F 8 , and Group 2 received 15-20 mL of 20% C 3 F 8 . Results: The median intraocular gas duration was 31 days in Group 1 and 34 in Group 2. The median letter gains in corrected distance visual acuity for the 26 th postoperative week were 20 letters in Group 1 and 12.5 in Group 2. The median intraocular pressure was normal in both groups. Primary anatomical success was 11/13 in both groups. Conclusions: The use of C 3 F 8 gas in a small undiluted volume is an alternative that slightly reduces the duration of the gas without negatively affecting the anatomical and visual response.

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Use of axial length to estimate the vitreous chamber volume in pseudophakic

Cited by 7 publications

References 11 publications

Clinical Performance Comparison of Ultrahigh-speed Dual Pneumatic Vitrectomy Probes: Is Faster and Smaller Better?

Clinical Performance Comparison of Ultrahigh-speed Dual Pneumatic Vitrectomy Probes: Is Faster and Smaller Better?

VIVEX: A Formula for Calculating Individual Vitreous Volume: A New Approach Towards Tailored Patient Dosing Regime in Intravitreal Therapy

Influence of the dilution method on the intraocular duration of C3F8 in vitrectomy for macular hole: a randomized clinical trial

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