2007
DOI: 10.1097/01.prs.0000245336.83934.e0
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Use of Botulinum Toxin Type A to Prevent Widening of Facial Scars

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Cited by 19 publications
(38 citation statements)
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“…Scars hypertrophy and widen when stretching mechanical forces are applied to resilient newly formed collagen before it reaches final maturity, a process that can take several months before being completed (38,39). Tensile distracting forces can be caused by factors such as muscle pull, elastic forces of adjacent skin, and external pressure (38,39). Widening of scars is thus mainly the result of mechanical influences on resilient and, as yet, immature collagen.…”
Section: Discussionmentioning
confidence: 99%
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“…Scars hypertrophy and widen when stretching mechanical forces are applied to resilient newly formed collagen before it reaches final maturity, a process that can take several months before being completed (38,39). Tensile distracting forces can be caused by factors such as muscle pull, elastic forces of adjacent skin, and external pressure (38,39). Widening of scars is thus mainly the result of mechanical influences on resilient and, as yet, immature collagen.…”
Section: Discussionmentioning
confidence: 99%
“…This concept is probably validated by the outcome of healing wounds relative to the lines of Langer. These lines lie perpendicular to the tension vector of underlying muscular contraction (38,39). Anecdotal evidence suggests that incisions created parallel to skin tension lines rarely form abnormal scars.…”
Section: Discussionmentioning
confidence: 99%
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