Use of butorphanol, fentanyl, and ketamine as co-induction agents with propofol for laryngeal mask airway insertion: A comparative study

Palanisamy, Nagalakshmi; Sundararajan, Leo; Uthirapathi, S

doi:10.4103/aer.aer_104_18

Cited by 6 publications

(4 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…On arrival in operating room large bore intravenous cannula was placed under local infiltration. General anesthesia was begun with coinduction 10,11 by injection nalbuphine 10mg plus midazolam in dose of 0.01mg/kg. Inj.…”

Section: Methodsmentioning

confidence: 99%

Anaesthesia Concern in High-Risk Cases Under-Going Ambulatory Laparoscopic Cholecystectomy

Maqbool¹,

Alam²,

Draz³

et al. 2021

J. Bahria Univ. Med. Dent. Coll.

View full text Add to dashboard Cite

Objective:To evaluate pre-operative implications, anesthetic management and post-operative anesthetic concerns in patientswith co-morbid diseases undergoing ambulatory laparoscopic cholecystectomy under general anesthesia. Study Design and setting:Retrospective study was conducted at Rawal Institute of Health Sciences, Islamabad from 8thOct 2017 to 5th Nov 2018. Methodology:Total one hundred and twelve patients were placed in American society of Anaesthesiologist (ASA) classII, III & IV (medically optimized) on pre-operative evaluation for ambulatory laparoscopic cholecystectomy. Generalanesthesia was administered with co-induction (nalbuphine 0.1mg/kg plus midazolam 0.01mg/kg) tracheal intubationfacilitated by 0.15mg/kg cis-atracurium. Post-operatively on clinical status evaluation and Post Anesthesia Discharge score,patients were shifted to respective ward /intensive care. Statistical analysis was done by SPSS v.21. Results:Pre-operatively medical and cardiologist evaluation was taken in 34(30.35%) and 42(37.5%) cases respectivelywhereas consultant anesthesiologist reviewed all cases. In study single case was converted to open method due to mirrizisyndrome and adhesions creating difficult laparoscopic dissection in 9(8.03%) of cases. Post-operatively in single caseatrial fibrillation with fast ventricular response noted followed by sudden bradycardia, managed and sinus rhythm restored,whereas in other case of ischemic heart disease with viral respiratory infection, needed ventilatory support after 2 hoursdue to respiratory distress and weaned off after 24hrs. In the study 76(67.9%) cases were shifted post-operatively to surgical ward and 36 cases (32.1%) needed intensive care treatment. Conclusion:Laparoscopic cholecystectomy in patients with co-morbid states requires balanced anesthetic technique considering consequences of pneumoperitoneum to decrease morbidity.

show abstract

Section: Methodsmentioning

confidence: 99%

Anaesthesia Concern in High-Risk Cases Under-Going Ambulatory Laparoscopic Cholecystectomy

Maqbool¹,

Alam²,

Draz³

et al. 2021

J. Bahria Univ. Med. Dent. Coll.

View full text Add to dashboard Cite

show abstract

“…However, unlike propofol, it acts as a sympathetic cardiorespiratory stimulant and has pain-relieving properties [6]. In the literature, several studies have shown that hemodynamic stability can be achieved with the combined use of ketamine and propofol in pediatric cases under general anesthesia with LMA [7][8][9][10]. However, most of those studies involved sedation and general anesthesia for non-specific surgical indications and were conducted on different patient cohorts consisting of both pediatric and adult groups.…”

Section: Introductionmentioning

confidence: 99%

The effect of ketofol anesthesia on intraocular pressure in pediatric strabismus surgery

Kılıç,

Gürsoy,

Bilir

et al. 2024

J Surg Med

View full text Add to dashboard Cite

Background/Aim: Keeping intraocular pressure (IOP) within normal limits is an important goal in the anesthetic management of pediatric strabismus surgery. While propofol is commonly used as an induction agent since it provides smooth laryngeal mask insertion, it has the undesirable side effect of dose-dependent cardiorespiratory depression. On the other hand, ketamine acts as a sympathetic cardiorespiratory stimulant; however, its effect on IOP is controversial. The aim of this study was to determine the effect of the combination of ketamine and propofol (ketofol) on IOP in pediatric strabismus surgery compared to propofol alone. Methods: Participants included patients aged between 2 and 18 years who underwent strabismus surgery. They were divided into two groups according to type of anesthesia induction: propofol and ketofol. Patient characteristics, surgical data, hemodynamic parameters, oculocardiac reflex (OCR), and IOP were compared between the two groups. Results: Forty-five children with a mean age of 7.7 years were enrolled in the study. The patients were assigned into two groups: propofol alone (n=26) and ketofol (n=19). The groups were similar in patient characteristics, surgical data, and hemodynamic parameters (P<0.05 for each). IOP was measured at four points: before anesthesia, at 1 minute following induction, at 3 minutes following laryngeal mask airway (LMA) insertion, and at the end of surgery. All IOP values were within normal limits. No significant differences in mean IOP values were found between the groups (P>0.05 for each). There was also no significant difference in OCR between the groups (P=1.000). Conclusions: Compared to propofol alone, ketofol had a similar effect on IOP, OCR, and hemodynamic parameters. These results suggest that ketofol can be safely used in the induction of anesthesia in pediatric patients undergoing strabismus surgery.

show abstract

“…12 For this sake different co-induction agents have been used with propofol, these include ketamine, fentanyl and butorphanol. 13 Ketamine has multidimensional clinical effects. It has gained its place as a co-induction agent.…”

Section: Introductionmentioning

confidence: 99%

Frequency of excellent Laryngeal mask airway insertion conditions in children undergoing elective surgery: A comparison of propofol with ketofol.

Ahmad¹,

Tariq²,

Sagheer³

et al. 2020

TPMJ

View full text Add to dashboard Cite

Objectives: The laryngeal mask airway is used for provision of anesthesia for various surgical procedures as well as in emergency management of airway. It is a useful rescue tool in cases of failed intubation. Its insertion is associated with lesser complications. With advancement in medical equipment new versions of LMA with additional benefits are available. In this study evaluation of frequency of excellent LMA insertion conditions with use of ketofol or propofol as induction agent has to be evaluated. Purpose of the study is to identify which agent will provide favourable conditions for insertion, with least complications. Study Design: Randomized control trial. Setting: Departments of Anesthesia and Intensive Care Allied Hospital and Aziz Fatimah Hospital, Faisalabad. Period: From 01-01-2017 to 30-06-2018. Material & Methods: Approval from ethical review committee was obtained. 230 children presenting for elective surgery were enrolled into study using non-probability consecutive sampling. Two groups consisting of 115 each were generated by randomization. Group P received propofol and Group PK received 2:1 propofol ketamine mixture. Ease of LMA insertion was assessed on the basis of degree of muscle relaxation and adverse reactions to LMA insertion. Data was collected and analysed using SPSS version 18. Results: Results were presented in terms of frequency of excellent LMA insertion conditions. It showed that ketofol provides better LMA insertion as compared to propofol alone with p value of 0.007, which is significant. Conclusion: The study concluded that use of ketofol provides excellent insertion conditions for LMA insertion in children presenting for elective surgery.

show abstract

Use of butorphanol, fentanyl, and ketamine as co-induction agents with propofol for laryngeal mask airway insertion: A comparative study

Cited by 6 publications

References 16 publications

Anaesthesia Concern in High-Risk Cases Under-Going Ambulatory Laparoscopic Cholecystectomy

Anaesthesia Concern in High-Risk Cases Under-Going Ambulatory Laparoscopic Cholecystectomy

The effect of ketofol anesthesia on intraocular pressure in pediatric strabismus surgery

Frequency of excellent Laryngeal mask airway insertion conditions in children undergoing elective surgery: A comparison of propofol with ketofol.

Contact Info

Product

Resources

About