Colorectal cancer (CRC) is the one of the most health problem. In 2020, CRC is the third most common cancer and the second cancer leading causes of cancer-related death in both sexes worldwide, accounting for an estimated 916,000 deaths and 1.93 million diagnoses, comprising over 9.4% of the premature deaths attributable to cancer [1]. The burden of CRC in Thailand is similarly significant, in 2023, 21,103 new cancer cases and 11,464 cancer deaths [2]. In addition, there has been a rising trend of this disease in Thailand same as worldwide. This rise in CRC can be attributed to western lifestyle, dietary, smoking, aging, obesity, lack of physical exercise [3]. Nowadays, standard treatments for CRC including surgery, chemotherapy, radiotherapy, and combination method. Advancements