Use of Condensed Nanofat Combined With Fat Grafts to Treat Atrophic Scars

Gu, Zhenhua; Li, Yirun; Li, Hua

doi:10.1001/jamafacial.2017.1329

Cited by 78 publications

(64 citation statements)

References 44 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Skin pieces and cells were fixed and stained according to the standard protocol. [30] Briefly, slides were washed four times with deionized water and then were incubated in ammoniacal silver solution for 12 hours at 25°C. Following thorough washing in deionized water, slides were incubated in hypo solution for 5 minutes.…”

Section: Masson-fontana Ammoniacal Silver Stainingmentioning

confidence: 99%

Isoliquiritigenin inhibits melanogenesis, melanocyte dendricity and melanosome transport by regulating ERK‐mediated MITF degradation

Cao

et al. 2019

Experimental Dermatology

View full text Add to dashboard Cite

Isoliquiritigenin (ISL), a flavonoid component from the hydrolysis products of licorice root. It has been reported that ISL inhibited melanogenesis by suppressing the tyrosinase activity in human melanocytes. Recently, ISL was found to induce melanin degradation in human epidermal keratinocytes. However, the role of ISL in pigmentation is not fully understood. In the current study, we aimed to investigate the effects of ISL on pigmentation, and further explored the underlying mechanism. Our results suggested that ISL suppressed basal and α‐MSH‐, ACTH‐ and UV‐induced melanin synthesis, in addition to inhibiting melanocyte dendricity and melanosome transport. ISL played these roles mainly by activating the extracellular signal‐regulated protein kinase pathway. Once activated, it induced microphthalmia‐associated transcription factor degradation and decreased the expression of tyrosinase, TRP‐1, DCT, Rab27a and Cdc42, finally inhibited melanogenesis, melanocyte dendricity and melanosome transport. Our findings suggested that ISL exhibited no cytotoxicity in our research, it may prove quite useful as a safer natural skin‐whitening agent.

show abstract

Section: Masson-fontana Ammoniacal Silver Stainingmentioning

confidence: 99%

Isoliquiritigenin inhibits melanogenesis, melanocyte dendricity and melanosome transport by regulating ERK‐mediated MITF degradation

Cao

et al. 2019

Experimental Dermatology

View full text Add to dashboard Cite

show abstract

“…There has also been an increased interest in so-called nanofat injections, which involves highly emulsified fat, used to improve skin texture, scars, and other cutaneous issues. 6 The author does not have any clinical experience using nanofat and defers this expertise to his colleagues who perform this procedure. He has observed that after many years doing fat transfer, there is a finer texture to the skin under areas in which fat has been transplanted.…”

mentioning

confidence: 99%

Fat Grafting for Facial Contouring

Lam¹

2019

Facial plast Surg

View full text Add to dashboard Cite

Fat grafting is a safe, effective method for facial rejuvenation if used to restore lost facial volume, but it is not as a method to correct cutaneous deformities and rhytids, or to counteract gravitational effects. The most significant postoperative complication is weight gain that can make a face look overinflated. Accordingly, it is important to select a safe and appropriate candidate. This article outlines who is a suitable prospect for fat grafting and juxtaposes the two methods of facial volume restoration: fat grafting versus injectable fillers. Then a detailed exposition of the operative technique is outlined, including anesthesia, harvesting, processing, and injection. Finally, this article concludes with a description of the postoperative course and the management of potential complications.

show abstract

“…Adipose-derived mesenchymal stem cell therapy in the treatment of knee osteoarthritis: a randomized controlled trial [144] 2019 derer der Wundheilung [5,74,[130][131][132], zur Behandlung von Verbrennungen [131,133], zur Verhinderung von unschöner Narbenbildung [134,135] und zur Förderung der Nervenregeneration [136][137][138]…”

Section: Klinische Studie Jahr Zell-ursprungunclassified

Stammzellen in der Regenerativen Medizin – Translationale Hürden und Möglichkeiten zur Überwindung

Klietz

Kückelhaus

Kaiser³

et al. 2020

Handchir Mikrochir Plast Chir

View full text Add to dashboard Cite

ZusammenfassungDer Einsatz von mesenchymalen Stammzellen in der regenerativen Medizin wird immer populärer. Nichtsdestotrotz ist ihre Anwendung im klinischen Alltag noch immer limitiert. Zahlreiche ethische, rechtliche und translationale Probleme sowie Ungewissheit bzgl. der Sicherheit hemmen noch immer die Entstehung von entsprechenden Therapien aus vielversprechenden wissenschaftlichen Ansätzen.Diese Arbeit soll die Hauptprobleme bei der Translation von stammzellbasierten Therapien aus der Grundlagenforschung und Präklinik in den klinischen Alltag darstellen, sowie Ansätze aufzeigen, diese zu überwinden.

show abstract

Use of Condensed Nanofat Combined With Fat Grafts to Treat Atrophic Scars

Cited by 78 publications

References 44 publications

Isoliquiritigenin inhibits melanogenesis, melanocyte dendricity and melanosome transport by regulating ERK‐mediated MITF degradation

Isoliquiritigenin inhibits melanogenesis, melanocyte dendricity and melanosome transport by regulating ERK‐mediated MITF degradation

Fat Grafting for Facial Contouring

Stammzellen in der Regenerativen Medizin – Translationale Hürden und Möglichkeiten zur Überwindung

Contact Info

Product

Resources

About