Use of Dietary Supplements for Cognitive Health

Laditka, James N.; Laditka, Sarah B.; Tait, Elizabeth M.; Tsulukidze, Maka

doi:10.1177/1533317511435662

Cited by 16 publications

(8 citation statements)

References 48 publications

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“… 31 In one study, Laditka et al found that most of adults used supplements to treat or cure their cognitive problems rather than to prevent them. 32 Hence, this study provides scientific evidence of beneficial effect of natural herbs, ie, PM extract in improving cognitive function and psychosocial parameter.…”

Section: Discussionmentioning

confidence: 73%

The effect of Polygonum minus extract on cognitive and psychosocial parameters according to mood status among middle-aged women: a randomized, double-blind, placebo-controlled study

Shahar

Aziz

Ismail

et al. 2015

CIA

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BackgroundPolygonum minus (PM) or locally known in Malaysia, as “kesum” is rich in micronutrients and natural antioxidants. However, its beneficial effect on outcome associates with oxidative stress including cognitive function is yet to be discovered. We assessed the efficacy of PM extract (LineMinus™) on cognitive function and psychosocial status among middle-aged women in Klang Valley of Malaysia.MethodsA randomized, double-blind, placebo-controlled trial among 35 healthy middle-aged women was performed, and subjects were randomized to receive either 250 mg PM or placebo of 100 mg maltodextrin each were taken twice daily for 6 weeks. Subjects were assessed for neuropsychological test, psychosocial status, and anthropometric at baseline, week 3, and week 6. Biomarkers were also determined at baseline and week 6.ResultsThe supplementation of PM showed significant intervention effect on Digit Span test (P<0.05) social functioning domain of 36-Item Short Form Health Survey (P<0.05) among subjects with mood disturbance. While, among subjects with good mood, PM supplementation improved Wechsler Abbreviated Scale of Intelligence (WASI) for IQ verbal (P=0.016) and Full Scale IQ of WASI (P=0.004). There were no adverse effects reported for the supplementation as indicated using biomarkers, including liver function and clinical symptoms.ConclusionSupplementation of PM is safe to be consumed for 6 weeks, with potential benefits to attention, short-term memory, improved quality of life, and mood, as well as IQ.

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Section: Discussionmentioning

confidence: 73%

The effect of Polygonum minus extract on cognitive and psychosocial parameters according to mood status among middle-aged women: a randomized, double-blind, placebo-controlled study

Shahar

Aziz

Ismail

et al. 2015

CIA

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“…Participants were predominantly adults with a small number of studies focussed on older adults 44,57,65,94,95,105,110,113,114 , children 45,58,63,68,73,97,103,106,115,116 , adolescents 41,97 , or all age groups 61,99,112 . More than half of the studies included users of various types of CM (n = 45) 31,35,36,38,41–43,50,51,54,57–59,61–63,65,66,68,72,73,75,76,80–82,85,88,89,96,97,102–113,115,116 , while others were limited to users of specific types of CM such as herbs and/or supplements 32–34,37,44–47,52,53,55,56,60,64,67,69–71,74,77–79,83,86,87,92–95,98–101,109,114 , yoga 48,91 , tai chi 49,90 , mind-body medicine 40 , practitioner-provided CM 39 , or local traditional medicine 84 .…”

Section: Resultsmentioning

confidence: 99%

Disclosure of complementary medicine use to medical providers: a systematic review and meta-analysis

Foley

Steel

Cramer

et al. 2019

Sci Rep

162

139

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Concomitant complementary medicine (CM) and conventional medicine use is frequent and carries potential risks. Yet, CM users frequently neglect to disclose CM use to medical providers. Our systematic review examines rates of and reasons for CM use disclosure to medical providers. Observational studies published 2003–2016 were searched (AMED, CINAHL, MEDLINE, PsycINFO). Eighty-six papers reporting disclosure rates and/or reasons for disclosure/non-disclosure of CM use to medical providers were reviewed. Fourteen were selected for meta-analysis of disclosure rates of biologically-based CM. Overall disclosure rates varied (7–80%). Meta-analysis revealed a 33% disclosure rate (95%CI: 24% to 43%) for biologically-based CM. Reasons for non-disclosure included lack of inquiry from medical providers, fear of provider disapproval, perception of disclosure as unimportant, belief providers lacked CM knowledge, lacking time, and belief CM was safe. Reasons for disclosure included inquiry from medical providers, belief providers would support CM use, belief disclosure was important for safety, and belief providers would give advice about CM. Disclosure appears to be influenced by the nature of patient-provider communication. However, inconsistent definitions of CM and lack of a standard measure for disclosure created substantial heterogeneity between studies. Disclosure of CM use to medical providers must be encouraged for safe, effective patient care.

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“…For increasing numbers seeking to augment their diets for cognitive health, factors such as convenience, cost, and concerns about long-term effects of methyl mercury may motivate the use of fish oil supplements (FOSs) to replace or augment dietary consumption of marine sources of n-3 PUFAs [1]. …”

Section: Introductionmentioning

confidence: 99%

Association of fish oil supplement use with preservation of brain volume and cognitive function

Daiello

Gongvatana

Dunsiger

et al. 2014

Alzheimer's & Dementia

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Objective The aim of this study was to investigate whether the use of fish oil supplements (FOSs) is associated with concomitant reduction in cognitive decline and brain atrophy in older adults. Methods We conducted a retrospective cohort study to examine the relationship between FOS use during the Alzheimer’s Disease Neuroimaging Initiative and indicators of cognitive decline. Older adults (229 cognitively normal individuals, 397 patients with mild cognitive impairment, and 193 patients with Alzheimer’s disease) were assessed with neuropsychological tests and brain magnetic resonance imaging every 6 months. Primary outcomes included (1) global cognitive status and (2) cerebral cortex gray matter and hippocampus and ventricular volumes. Results FOS use during follow-up was associated with significantly lower mean cognitive subscale of the Alzheimer’s Disease Assessment Scale and higher Mini-Mental State Examination scores among those with normal cognition. Associations between FOS use and the outcomes were observed only in APOE ε4–negative participants. FOS use during the study was also associated with less atrophy in one or more brain regions of interest.

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Use of Dietary Supplements for Cognitive Health

Cited by 16 publications

References 48 publications

The effect of Polygonum minus extract on cognitive and psychosocial parameters according to mood status among middle-aged women: a randomized, double-blind, placebo-controlled study

The effect of Polygonum minus extract on cognitive and psychosocial parameters according to mood status among middle-aged women: a randomized, double-blind, placebo-controlled study

Disclosure of complementary medicine use to medical providers: a systematic review and meta-analysis

Association of fish oil supplement use with preservation of brain volume and cognitive function

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