Use of eggshells as a raw material for production of calcium preparations

Dolińska, Barbara; Marta, Jelińska; Szulc-Musioł, Beata; Ryszka, Florian

doi:10.17221/59/2016-cjfs

Cited by 27 publications

(9 citation statements)

References 12 publications

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“…Therefore, the need for alternative uses of eggshells seemed beneficial. Not only does eggshell calcium provide the best natural calcium source—better than that of limestone or coral sources (Lee and Oh, 2003, Ruff et al, 2012, Uraz et al, 2013)—it is also better absorbed by the body (Dolińska et al, 2016). Eggshell powder has been reported as safe for use by several European and Asian animal and human studies (Ruff et al, 2012, Uraz et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

Histomorphometric evaluation of a nano-sized eggshell-containing supplement as a natural alloplast: An animal study

Salama

Khashaba

Rouby

2019

The Saudi Dental Journal

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BackgroundLimitations of autogenous grafts have dictated the need for development of new biomaterials that can serve as allografts. A paradigm shift directed manufacturers to revert to nature in the search for such allografts. This study aimed to evaluate an eggshell-based supplement, Membrell’s® BONEhealth Plus D3 & K2, indicated to support bone mineral density, as a natural bone graft material.MethodsTwelve 5 × 10 × 1 mm full-thickness cranial bone defects were created in six adult male New Zealand rabbits. Six defects were filled with Membrell’s® BONEhealth™ Plus D3 & K2, and the others were left empty as control. The animals were sacrificed 14 days postoperatively. The defects were dissected and prepared for histological assessment. Bone formation was compared both qualitatively and quantitatively. The area percent of newly-formed bone was evaluated in five successive regions using image analysis. Statistical analysis was performed using unpaired t-test. Differences between the two groups were considered significant at p ≤ 0.05.ResultsCranial bone defects filled with the nano-sized eggshell powder “Membrell’s® BONEhealth™ Plus D3 & K2” revealed significantly higher levels of osteoid, newly-formed, regularly-arranged bone trabeculae in the center of the defects (47.37% ± 1.12) compared to the control defects (21.6% ± 4.92), which revealed no bone formation. A rapid rate of resorption of the nano-sized eggshell powder and consequently a rapid osteogenic effect was evident.ConclusionsThe eggshell-based graft powder, Membrell’s® BONEhealth™ Plus D3 & K2, is a biocompatible material which has the potential to enhance new bone formation.

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Section: Introductionmentioning

confidence: 99%

Histomorphometric evaluation of a nano-sized eggshell-containing supplement as a natural alloplast: An animal study

Salama

Khashaba

Rouby

2019

The Saudi Dental Journal

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“…This procedure involved roasting the eggshells (for 2 h at 120 °C) with citric acid, followed by tableting. The synthetic calcium carbonate tablet was prepared by forming a granulate followed by drying at 60 °C for 24 h Calcium content from the calcium citrate extracted from eggshells was 100.0 ± 1.4 mg; and the amount found in the synthetic tablets 100.0 ± 2.7 mg Barbara et al 2016 …”

Section: Analysis Of the Various Methodologies Employed In Calcium Extraction From Eggshellsmentioning

confidence: 99%

Review on the extraction of calcium supplements from eggshells to combat waste generation and chronic calcium deficiency

Singh

Kelkar

Natarajan

et al. 2021

Environ Sci Pollut Res

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When faced with a plethora of issues, the possibility of one problem becoming the solution of another is a rare, yet beneficial scenario. This report explores the prospect of viewing the accumulation of organic waste matter in India as a potential calcium reservoir to relieve the issue of calcium deficiency in the population. Waste generation has seen gradual growth, and it has created a problem of waste disposal. A large segment of the generated waste primarily consists of food waste which contains significant amounts of nutrients. Food waste such as eggshells, waste from shellfish, bones, and fish scales contain good amounts of bioavailable calcium, and large quantities of this discarded bioavailable calcium remain unused. Global studies show India to have significantly lower levels of calcium intake than the global average, thus increasing the risk of calcium deficiency-related diseases. Furthermore, research shows that for over the past half of the century, the intake of dietary calcium has declined drastically throughout India. This has led to chronic calcium deficiency-related diseases throughout most of the Indian population. Hence, development of calcium supplements from calcium-rich waste material has the potential to not only reduce the strain on waste management, but also to provide the calcium-deficient population with a cheaper alternative to traditional supplements. Owing to the abundance and ease of separation, eggshells have been chosen as the focus of the review. This review highlights and compares their extraction methods of providing cheap calcium supplements while reducing the amount of eggshell waste.

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“…In turn, Brun et al [35] reported that the best form of using chicken eggshells as a dietary supplement of Ca is to add them in the powdered form to, e.g., bread, pizza, and spaghetti, as it caused little changes in their texture and no changes in their taste. Calcium-enriched foods should have similar physical and sensory properties to their non-enriched counterparts [13,[36][37][38].…”

Section: Determination Of Sensory Evaluationmentioning

confidence: 99%

Impact Mineralization of Chokeberry and Cranberry Fruit Juices Using a New Functional Additive on the Protection of Bioactive Compounds and Antioxidative Properties

et al. 2020

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Chicken eggshells can be used as an attractive dietary source of mineral compounds, including calcium (Ca). However, the effects of chicken eggshell powder (CESP) on berry fruit juices have not been studied to date. Therefore, the objective of this study was to evaluate the effect of its addition to juices from chokeberry and cranberry on their phytochemical properties. The juices were determined for contents of polyphenols (determined by ultra-efficient liquid chromatography coupled with a mass detector (UPLC-PDA-ESI-MS/MS)), macro- and microelements (by inductively coupled plasma - optical emission spectrometry (ICP-OES)), and organic acids (by high-performance liquid chromatography (HPLC-PDA)) as well as for their antioxidative activity by radical scavenging capacity (ABTS) and ferric reducing antioxidative power (FRAP) assay, color profile (CIE L* a* b* system), and sensory attributes. The study results demonstrate that CESP addition to chokeberry and cranberry juices enriched them with minerals and increased their Ca content 25.7 times and 66.3 times, respectively, compared to the control samples. Juices supplementation with CESP significantly decreased their acidity and total organic acids content as well as increased their pH value. Chokeberry and cranberry juices supplementation with 1% CESP caused no significant changes in the amount of precipitate and their color, but it significantly improved their taste. For this reason, CESP addition in the amount of up to 1% can be suggested as the optimal supplementation of berry fruit juices. The study also demonstrated that CESP addition in the amount of up to 1% caused no significant differences in the content of polyphenolic compounds and in the antioxidative activity of juices, which can be deemed important from the viewpoint of their putative health benefits. In addition, the heat treatment of juices contributed to only a 4% loss of polyphenolic compounds from the CESP-supplemented juices compared to the 6% loss from the non-supplemented juices.

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Use of eggshells as a raw material for production of calcium preparations

Cited by 27 publications

References 12 publications

Histomorphometric evaluation of a nano-sized eggshell-containing supplement as a natural alloplast: An animal study

Histomorphometric evaluation of a nano-sized eggshell-containing supplement as a natural alloplast: An animal study

Review on the extraction of calcium supplements from eggshells to combat waste generation and chronic calcium deficiency

Impact Mineralization of Chokeberry and Cranberry Fruit Juices Using a New Functional Additive on the Protection of Bioactive Compounds and Antioxidative Properties

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