Use of Electronic Health Record Clinical Decision Support Tools in Antimicrobial Stewardship Activities

Rush, Jordan; Postelnick, Michael; Schulz, Lucas T

doi:10.1007/s40506-015-0042-8

Curr Treat Options Infect Dis

2015

DOI: 10.1007/s40506-015-0042-8

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Use of Electronic Health Record Clinical Decision Support Tools in Antimicrobial Stewardship Activities

Jordan Rush

Michael Postelnick

Lucas T Schulz

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2019

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“…5 The use of the electronic medical record (EMR) and clinical decision support systems (CDSS) for antimicrobial stewardship has been reported widely in the United States and the international setting, and outcomes of such systems are well documented in the literature. [7][8][9][10][11][12][13] A recent survey conducted by the American Society of Health-System Pharmacists (ASHP) showed that 95% of hospitals have computerized prescriber-order-entry (CPOE) systems and of those, 39% of hospitals utilize clinical decision support for their ASPs. 14 There is a lack of literature documenting the use of CDSS and computerized surveillance systems for ASP in the Middle East.…”

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Implementation and outcomes of an advanced antimicrobial stewardship program at a quaternary care hospital in the United Arab Emirates

El-Lababidi

Mooty

Bonilla

et al. 2019

J Am Coll Clin Pharm

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Purpose The implementation of an advanced antimicrobial stewardship program (ASP) at a quaternary care hospital in the United Arab Emirates is described, including a report on the implementation and outcomes of the program. Methods This was a single‐center quasi‐experimental study to assess the impact of the ASP on antimicrobial use measures, ASP interventions performed, and clinical outcomes by comparing the data collected at baseline, from the third quarter (Q3) 1 July 2015 to the fourth quarter (Q4) of 31 December 2017, approximately 2 years following program implementation. Results From 1 July 2015 until 31 December 2017, the program reported a total direct cost savings estimated at $1 339 499, despite a significant increase in patient discharges and total patient‐days. The antimicrobial cost per inpatient‐day decreased by 32% from $47.2 to $32.3. Usage of monitored antimicrobials decreased despite an increase in patient census since hospital opening. Hospital‐onset Clostridioides difficile infection (CDI) rates decreased from 0.46 cases per 1000 patient days in 2015 to 0.12 cases per 1000 patient days in 2017 (P = 0.035, 95% CI 0.08 to 0.91). Hospital‐onset infections due to multidrug‐resistant organisms (MDROs) decreased from 2.39 cases per 1000 patient days in 2015 to 0.38 cases per 1000 patient days in 2017 (P = 0.05, 95% CI 0.09 to 0.28). Overall, the number of ASP interventions amounted to a total of 4123 interventions, with an acceptance rate of 91%. Conclusion The implementation of an advanced ASP at a quaternary care hospital in the United Arab Emirates was associated with a decrease in antimicrobial utilization, antimicrobial expenditure, and a reduction in hospital‐onset CDI and MDRO rates. To our knowledge, this is the first report describing the outcomes of an advanced ASP program at a quaternary care hospital utilizing real‐time surveillance software and CDSS in the Middle East.

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confidence: 99%

Implementation and outcomes of an advanced antimicrobial stewardship program at a quaternary care hospital in the United Arab Emirates

El-Lababidi

Mooty

Bonilla

et al. 2019

J Am Coll Clin Pharm

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Use of Electronic Health Record Clinical Decision Support Tools in Antimicrobial Stewardship Activities

Cited by 1 publication

References 33 publications

Implementation and outcomes of an advanced antimicrobial stewardship program at a quaternary care hospital in the United Arab Emirates

Implementation and outcomes of an advanced antimicrobial stewardship program at a quaternary care hospital in the United Arab Emirates

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