Use of EMLA cream as a topical anaesthetic before venepuncture procedures in field surveys: A practice that helps children, parents and health professionals

Gwetu, Thando P; Chhagan, Meera

doi:10.7196/samjnew.7797

Cited by 13 publications

(9 citation statements)

References 12 publications

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“…[Table 1]. Concerning the outcome variable, pain was measured using the VRS by two studies [16,19] the NRS by one study [18] and the VAS by two studies [17,19]. One of the reviewed studies [19] used two pain scales to measure pain; Oluwadun et al [19] employed the VRS and the VAS for all their participants; van Straten et al [18] on the other, created ordinal categories of patients pain from their NRS scores.…”

Section: Resultsmentioning

confidence: 99%

“…Regarding adverse effects, all four studies evaluated this outcome, and three observed no adverse reactions [16][17][18] with the various topical interventions. One study [19], on the other hand, discovered more adverse reactions with the 10% lidocaine treatment compared to the 5% EMLA treatment; blanching of the skin was noticed in both the treatment groups and the control group [Table 2].…”

Section: Resultsmentioning

confidence: 99%

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Pain Attenuation During Peripheral Venous Catheterisation and Venipuncture Among an African Study Population: A Narrative Review.

Aiseosa

2024

Preprint

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Introduction:Pain associated with peripheral venous catheter (PVC) insertion and venipuncture can be a significant source of discomfort, particularly for children. The use of topical anaesthetic preparations before PVC insertion can reduce discomfort and enhance health-seeking behaviour. Objective:This review was aimed at assessing the efficacy of topical anaesthesia to reduce pain during PVC insertion compared to placebo or no treatment, and the associated adverse effects with the use of topical anaesthetic preparations among the African population. Methods:This review was conducted using a systematic literature search of the following databases and registers:: PubMed, NDLTD, OATD, TROVE, LILACS, Scopus, The Cochrane Library, CINAHL & MEDLINE [via EBSCOhost], Africa Journal Online (AJOL), Google Scholar, and MedNar was conducted between November and December 2023. Prospective observational studies, randomised controlled trials, case-control studies, longitudinal studies, theses and dissertations were considered in these searches. A total of four studies and 448 respondents participated in the review. Result:All studies investigated the efficacy of various topical agents, including 5% EMLA and 10% lidocaine cream, and demonstrated a significant reduction in pain with topical anaesthesia compared to placebo or no treatment. The adverse/side effect profile was generally favourable, with no major adverse reactions reported. Conclusion:Topical anaesthesia is a valuable tool in reducing procedural pain during peripheral venous catheterization and venipuncture in the African population. This review establishes its superiority over placebo or no treatment. Specifically, 10% lidocaine outperforms 5% EMLA in minimizing procedural pain with minimal side effects. Further research is needed to explore alternative preparations for cases of adverse reactions and ineffective anaesthesia.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Pain Attenuation During Peripheral Venous Catheterisation and Venipuncture Among an African Study Population: A Narrative Review.

Aiseosa

2024

Preprint

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“…Systemische Nebenwirkungen sind sehr selten und können nur bei einer deutlichen Überdosierung auftreten. Die Anwendung ist auf die intakte Haut beschränkt 7 .…”

Section: Zaubercreme – Die Haut Schützenunclassified

Gib mir Fünf – Blutabnahme leicht gemacht

Neugebauer¹,

Lubner-Langener²,

Heinrich³

et al. 2023

Zeitschrift für Komplementärmedizin

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SummarySelbst kleinere medizinische Interventionen wie das Impfen oder Blutabnehmen lösen bei jungen Patienten oft Angst und Stress aus. Das führt häufig dazu, dass die Kinder festgehalten werden müssen. Das „Gib mir Fünf“-Konzept – bestehend aus Kommunikation, Zauberpflaster, Nähe, Fokus und Brummel – bietet eine Strategie, um Schmerz und Angst bei prozeduralen Schmerzen zu verringern und Blutabnahme oder Impfung bei Kindern atraumatisch durchzuführen.

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“…Unfortunately, there are some factors leading to infrequent use of topic local anesthesia. More specifically, it takes considerable time to produce a sufficient effect [ 14 – 16 ], higher cost [ 17 ], and may cause allergic contact dermatitis [ 18 , 19 ].…”

Section: Introductionmentioning

confidence: 99%

Efficacy and safety of vapocoolant spray for vascular puncture in children and adults: A systematic review and meta-analysis

et al. 2023

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Objective The aim was to evaluate the effectiveness and safety of the vapocoolants for vascular puncture in children and adults. Method The search was carried out in PubMed, Web of Science, Embase and The Cochrane Library, from inception to March 2022. Randomized controlled trials comparing vapocoolants to control conditions for participants received intravenous cannulation or arterial puncture were included. Two reviewers independently performed selection of studies, data extraction, and assessment of risk of bias. The analysis was performed using fixed or random-effects model with mean differences or standardized mean difference and risk ratios. Results A total of 25 studies involving 3143 participants were included. Compared with control conditions, vapocoolants may not decrease the pain of patients with arterial puncture (SMD = -0.36, 95% CI = -0.92 to -0.19, P = 0.20), but may more effectively relieve pain for adults received vein puncture (SMD = -0.65, 95% CI = -0.85 to -0.45, P < 0.00001). The application of vapocoolant increased the procedural difficulty of medical personnel (RR = 2.49, 95% CI = 1.62 to 3.84, P<0.000 1) and participants were more willing to use the spray in the future (RR = 1.88, 95% CI = 1.34 to 2.64, P = 0.0002). There was no significant difference for the first attempt success rate of the procedure and the occurrence of adverse events. Conclusions Vapocoolant spray may relieve pain in adults received vein puncture and cannot cause severe side effects, but is ineffective in children. It also had no effect on patients with arterial puncture. In addition, the application of spray increases procedural difficulties for medical professionals, but does not decrease first attempt success rate, and many patients would like to use the spray again for pain relief in the future. Thus, more rigorous and large-scale studies are needed to determine its effectiveness in vascular access.

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Use of EMLA cream as a topical anaesthetic before venepuncture procedures in field surveys: A practice that helps children, parents and health professionals

Cited by 13 publications

References 12 publications

Pain Attenuation During Peripheral Venous Catheterisation and Venipuncture Among an African Study Population: A Narrative Review.

Pain Attenuation During Peripheral Venous Catheterisation and Venipuncture Among an African Study Population: A Narrative Review.

Gib mir Fünf – Blutabnahme leicht gemacht

Efficacy and safety of vapocoolant spray for vascular puncture in children and adults: A systematic review and meta-analysis

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