Use of enhancers in the HPTLC fluorescence analysis of thiols

Ling, Bowen; Baeyens, W. R. G.; Castillo, B. del; Stragier, K.; Marysael, H.; Moerloose, P. De

doi:10.1016/0731-7085(89)80181-5

Cited by 15 publications

(2 citation statements)

References 17 publications

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“…The derivatization using ABD-F as a pre-column fluorogenic reagent for thiols was applied to the determination of biologically and pharmacologically interesting thiols, including glutathione, coenzyme A, acetylcysteine and captopril etc. (Ling et al, 1989(Ling et al, , , 1990b, chloramphenicol (Yamato et al, 1990), total homocysteine, cysteine cystinylglycine and glutathione using tri-n-butylphosphine (Reddy and Behnke, 1997). ABD-F was used for the derivatization with differentiation of cysteine residues in proteins.…”

Section: For Thiolsmentioning

confidence: 99%

Fluorogenic and fluorescent labeling reagents with a benzofurazan skeleton

Uchiyama

Santa

Okiyama

et al. 2001

Biomedical Chromatography

152

101

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Fluorogenic and fluorescent labeling reagents having a benzofurazan (2,1,3-benzoxadiazole) skeleton such as 4-fluoro-7-nitro-2,1,3-benzoxadiazole (NBD-F), 4-N,N-dimethylaminosulfonyl-7-fluoro-2,1,3-benzoxadiazole (DBD-F), 4-aminosulfonyl-7-fluoro-2,1,3-benzoxadiazole (ABD-F), ammonium 7-fluoro-2,1,3-benzoxadiazole-4-sulfonate (SBD-F), 4-hydrazino-7-nitro-2,1,3-benzoxadiazole (NBD-H), 4-N,N-dimethylaminosulfonyl-7-hydrazino-2,1,3-benzoxadiazole (DBD-H), 4-nitro-7-N-piperazino-2,1,3-benzoxadiazole (NBD-PZ), 4-N,N-dimethylaminosulfonyl-7-N-piperazino-2,1,3-benzoxadiazole (DBD-PZ), 4-(N-chloroformylmethyl-N-methyl)amino-7-N,N-dimethylaminosulfonyl-2,1,3-benzoxadiazole (DBD-COCl) and 7-N,N-dimethylaminosulfonyl-4-(2,1,3-benzoxadiazolyl) isothiocyanate (DBD-NCS) are reviewed in terms of synthetic method, reactivity, fluorescence characteristics, sensitivity and application to analytes.

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Section: For Thiolsmentioning

confidence: 99%

Fluorogenic and fluorescent labeling reagents with a benzofurazan skeleton

Uchiyama

Santa

Okiyama

et al. 2001

Biomedical Chromatography

152

101

View full text Add to dashboard Cite

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“…Compounds with native fluorescence are viewed as bright zones on a dark background under UV light. Substances without chromophores or colour that cannot be seen under UV-visible light can be visualized and made detectable by enhancing their fluorescence through post-chromatographic derivatization [13,15]. Derivatization is a technique used in TLC to change the properties of the sample by increasing detectability and/or visualization of the analyte.…”

Section: Chromatographic Methodsmentioning

confidence: 99%

Quantitative High Performance Thin Layer Chromatography for the Analysis of Herbal Medicines: Problems and Advantages

Agatonović-Kuštrin¹

2014

Mod Chem Appl

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Separation methods for captopril in pharmaceuticals and biological fluids

Mansour¹,

Danielson²

2012

J of Separation Science

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Captopril (CAP) is an orally active angiotensin‐converting enzyme (ACE) inhibitor and has been widely used for management of hypertension and congestive heart failure. CAP lacks an aromatic chromophore required for facile direct UV detection and also has two chiral centers. These factors can render the determination of CAP in complex matrices challenging. This review covers more than 20 years of analytical research on this drug, focusing mainly on pharmaceutical and biological applications. The primary separation techniques discussed are gas chromatography, liquid chromatography, and capillary electrophoresis. The structures of the CAP derivatizing agents as well as a table summarizing various HPLC methods are provided. A discussion of key recent chromatographic and electrophoretic methods for other ACE inhibitors is also present.

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Use of enhancers in the HPTLC fluorescence analysis of thiols

Cited by 15 publications

References 17 publications

Fluorogenic and fluorescent labeling reagents with a benzofurazan skeleton

Fluorogenic and fluorescent labeling reagents with a benzofurazan skeleton

Quantitative High Performance Thin Layer Chromatography for the Analysis of Herbal Medicines: Problems and Advantages

Separation methods for captopril in pharmaceuticals and biological fluids

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