“…[3,10] No difference in intra-operative pain was noted when bupivacaine without adrenaline was compared with lignocaine containing it, so the former can be used without vasoconstrictor. [4] A combination of 0.5% bupivacaine with adrenaline 1:200,000 when used gives similar results. [7] www.wjpr.net Vol 6, Issue 4, 2017.…”
Section: Discussionmentioning
confidence: 84%
“…[13] The maximum postoperative pain is usually experienced during the first 6-8 hours so the use of bupivacaine improves postoperative comfort and reduces the need for strong analgesics. [4,14] The number of analgesics required was 1 lesser with bupivacaine during the first 24 hours post operatively which was statistically highly significant. In view of this, there appears to be a definite place for the use of long acting local anaesthetics.…”
Section: World Journal Of Pharmaceutical Researchmentioning
confidence: 99%
“…Addition of a vasoconstrictor does not seem to prolong its duration of action. [4] This study was aimed to compare the efficacy of bupivacaine and lignocaine in the impacted lower third molar surgery by comparing time of onset and duration of anaesthesia, onset of postoperative pain, comparative pain evaluation, postoperative analgesic requirement and signs of systemic toxicity.…”
“…[3,10] No difference in intra-operative pain was noted when bupivacaine without adrenaline was compared with lignocaine containing it, so the former can be used without vasoconstrictor. [4] A combination of 0.5% bupivacaine with adrenaline 1:200,000 when used gives similar results. [7] www.wjpr.net Vol 6, Issue 4, 2017.…”
Section: Discussionmentioning
confidence: 84%
“…[13] The maximum postoperative pain is usually experienced during the first 6-8 hours so the use of bupivacaine improves postoperative comfort and reduces the need for strong analgesics. [4,14] The number of analgesics required was 1 lesser with bupivacaine during the first 24 hours post operatively which was statistically highly significant. In view of this, there appears to be a definite place for the use of long acting local anaesthetics.…”
Section: World Journal Of Pharmaceutical Researchmentioning
confidence: 99%
“…Addition of a vasoconstrictor does not seem to prolong its duration of action. [4] This study was aimed to compare the efficacy of bupivacaine and lignocaine in the impacted lower third molar surgery by comparing time of onset and duration of anaesthesia, onset of postoperative pain, comparative pain evaluation, postoperative analgesic requirement and signs of systemic toxicity.…”
“…Some authors found epinephrine to prolong anesthetic effect [4,7], while others did not [5,8]. We prefer to use epinephrine for reasons other than its possible effect on duration of action.…”
Section: Discussionmentioning
confidence: 97%
“…A somatic part arises from the body wall and is [4][5][6][7], although the actual differences were sometimes small and individual variations marked. We chose 0.5% bupivacaine because it was readily available and because the stronger 0.75% preparation is not recommended for infiltration anesthesia.…”
proteomics approach to Unravel the druggable proteins of the emerging pathogen Waddlia chondrophila and drug repositioning on its MurB protein, HELIYON,
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