This research assessed the impact of incorporating waste Polystyrene (PS) at replacement levels ranging from 5% to 50% in bitumen binder modification for sustainable asphalt. Rice husk ash (RHA) and de-silted sand served as filler and fine aggregate, respectively, with crushed granite acting as coarse aggregate. Various tests, encompassing penetration, viscosity, flash point, fire point, specific gravity, ductility, and the Marshall stability test, were conducted on the asphalt binder. In the case of the modified binder, the penetration, ductility, viscosity, and specific gravity exhibited a decline with increasing PS content, while the flash and fire points experienced an upward trend. The stability assessment revealed that at a 10% PS content, the asphalt exhibited suitable characteristics for heavy traffic (wearing course), with stability, flow, density, air void, void in mineral aggregates (VMA), and Void filled with bitumen (VFB) values of 6825N, 3.33mm, 2.362g/cm3, 4.52%, 18.21%, and 75.18%, respectively. Within the 15%-45% PS content range, the modified asphalt met the criteria for medium traffic (binder course). FTIR and SEM analyses confirmed the successful synthesis of PS-modified asphalt, demonstrating the encapsulation of PS microspheres on the binder's surface, forming a composite network structure in the asphalt. Consequently, it was concluded that this investigated modified asphalt derived from waste materials could be effectively utilized in constructing asphaltic pavement courses. These findings suggest the potential for the developed modified asphalt to serve as an economical road surfacing material, concurrently addressing pollution and environmental concerns associated with waste.