S exually transmitted infections (STIs) are prevalent, with current rates the highest ever reported in US history. 1 Sexually transmitted infections can have severe health consequences if left untreated 1 and are also costly; direct medical costs for chlamydia and gonorrhea alone are one billion dollars annually. 2 Sexually transmitted infection rates among young people are especially high; half of new STIs are diagnosed among individuals aged 15 to 24 years. 2 College students are likewise vulnerable to STIs 3,4 and represent a considerable 40% of the US population aged 18 to 24 years. 5 Expansion of high-quality secondary prevention strategies for STIs is recommended to mitigate the STI crisis in the United States. 6 We contend that expanded use of expedited partner therapy (EPT) for indicated STIs at college health centers (CHCs) is one such approach.Expedited partner therapy is the clinical practice of treating the sex partners of someone diagnosed with an STI without a health care examination. 7 Expedited partner therapy has been recommended by numerous medical and public health agencies given its ability to increase partner treatment and reduce reinfection, 4,7,8 and as of April 2021 is permissible or potentially allowable in all US states and territories. 9 Yet despite the known benefits, EPT provision rates are suboptimal. 10