“…In our study, 18 F-FDG PET/CT had excellent sensitivity of 100% and a good positive predictive value of 75% in the differential diagnosis of malignant and benign pancreatic cystic lesions. Similarly, 18 F-FDG PET/CT has outperformed conventional imaging in all previous studies concerning pancreatic cystic lesions-studies that were conducted on patients with IPMN (10,(18)(19)(20). Recently, Pedrazzoli et al (21) concluded that the decision on whether to perform prophylactic resectioning of IPMN in young patients fit for surgery should be guided by the International Consensus Guidelines (12), whereas PET should be performed in the case of older patients, those at increased surgical risk, and those for whom the feasibility of parenchyma-sparing surgery demands reliable preoperative exclusion of malignancy.…”