Use of fermented Chinese medicine residues as a feed additive and effects on growth performance, meat quality, and intestinal health of broilers

Abstract

IntroductionThe purpose of this research was to investigate how dietary supplementation with fermented herbal residues (FCMR) affected birds' development capacity, quality of meat, gut barrier, and cecum microbiota.Methods540 cyan-shank partridge birds aged 47 days were chosen and divided into two groups of six replicates each and 45 birds for each replicate. The control group (CON) received a basal diet, while the trial group decreased a basic diet containing 5% FCMR.Results and discussionThe findings revealed that the addition of FCMR decreased FCR and increased ADG in broilers (P < 0.05). Adding FCMR increased steaming loss in broiler chicken breasts (p < 0.05). Supplementation with FCMR significantly enhanced VH/CD and VH in the bird's intestine (jejunum, duodenum, and ileum) (p < 0.05). In addition, the addition of FCMR significantly down-regulated mRNA expression of INF-γ, IL-6, IL-1β, and TNF-α and up-regulated mRNA expression of ZO-1, Occludin, and Claudin (P < 0.05). Microbial 16S rDNA high-throughput sequencing study revealed that supplements with FCMR modified the cecum microbiota, and α-diversity analysis showed that supplementation with FCMR reduced the cecum bacterial abundance in broilers (P < 0.05). At the phylum level, the relative abundance of Spirochaetota increased considerably following FCMR supplementation (P < 0.05). The broiler cecum's close lot of Prevotellaceae_UCG-001 (P < 0.05), Desulfovibrio, Muribaculaceae, and Fusobacterium (p < 0.05) reduced when FCMR was supplemented. Supplementation with FCMR can promote growth capacity and maintain intestinal health in birds by enhancing gut barrier function and modulating the inflammatory response and microbial composition.

The effects of fermented feedstuff derived from Citri Sarcodactylis Fructus by-products on growth performance, intestinal digestive enzyme activity, nutrient utilization, meat quality, gut microbiota, and metabolites of broiler chicken

“…In another study, supplementing with 3 g/kg of Lichen Bacillus fermented product enhanced the body weight and average weight of birds compared to the control group ( 23 ). Our previous research also found that supplementing with 5% fermented medicinal herb residues enhanced the FW and ADG of broilers, while decreased their feed to meat ratio ( 24 ). Consistent with previous researchers, supplementing with a certain amount of FCSF significantly improved the FW and ADG of broilers, while significantly reduced their F/G, ADFI, and mortality.…”

Effects of different addition levels of CHM-JM113 on growth performance, antioxidant capacity, organ index, and intestinal health of AA broilers

“…Intestinal villus height (VH), crypt depth (CD) and VH/CD ratio are important indicators of intestinal structural integrity ( 49 ). Longer intestinal villus height and shallower crypt depth indicate better healthy digestion and absorption of microorganisms ( 10 ), improved intestinal mucosal differentiation, and enhanced capacity for digestion and absorption ( 50 ). Previous studies have found that adding probiotics, forsythia extract, natural pepper extract, and ellagic acid is an alternative to antibiotics in increasing the intestinal villus height of broilers ( 51 , 52 ).…”

Cordyceps militaris Extract and Cordycepin Alleviate Oxidative Stress, Modulate Gut Microbiota and Ameliorate Intestinal Damage in LPS-Induced Piglets

“…This increased relative abundance of Bacteroidota contributes to the maintenance of intestinal health and the alleviation of intestinal inflammation and LPS-induced systemic inflammation [45,46]. Previous studies have suggested that the supplementation of broiler chickens with fermented herbal residues (FCMRs) increases the relative abundance of cecal Spirochaetota, which facilitates the conversion of carbohydrates to volatile fatty acids (VFAs) to provide energy to the body [47,48]. In conclusion, the addition of CME and CPN prevented the decrease in the relative abundance of beneficial bacteria caused by LPS induction and increased the number of acid-producing bacteria.…”