Use of hemopatch as a sealant at the pancreaticojejunostomy to prevent postoperative pancreatic fistula. A randomized control trial

Abstract

treatment only (2 patients, 3.3%). Eight of the 16 patients with biliary complications went on to surgical resection (50%) compared to 26 of the 43 (60.4%) patients who did not have biliary complications. (c 2 =0.18, p = 0.67). Conclusion: Biliary complications during neoadjuvant therapy for pancreatic head cancer are relatively common, but do not significantly affect proceeding to surgical resection.

Big data and RCT's in surgical oncology: Impact on improving hepatopancreatobiliary cancer surgical care on the global stage

“…27 A recent RCT demonstrated that the use of a polyethylene glycol-coated hemostatic patch reduced the risk of a clinically relevant postoperative pancreatic fistula (CR-POPF) by 90%. 28 A large National Surgical Quality Improvement Program analysis of 7583 patients showed that routine placement of surgical drains decreased postoperative complications but prolonged drainage was associated with increased complications. 29 A randomized trial by Ke et al showed no difference in POPF rates between conventional limb reconstruction and Rouxen-Y reconstruction with an isolated pancreatic limb after a pancreatoduonectomy.…”

“…The recently published PANDA trial reported reduced rates of PPH with the “falciform wrap” technique 27 . A recent RCT demonstrated that the use of a polyethylene glycol‐coated hemostatic patch reduced the risk of a clinically relevant postoperative pancreatic fistula (CR‐POPF) by 90% 28 . A large National Surgical Quality Improvement Program analysis of 7583 patients showed that routine placement of surgical drains decreased postoperative complications but prolonged drainage was associated with increased complications 29 .…”