Use of His-Bundle Pacing for the Treatment of Left Bundle Branch Block-Induced Cardiomyopathy Following Orthotopic Heart Transplantation: A Case Report

Khaira, Kavita; Singh, Rajeev; Simon, Joel; Shirazi, Johnathan T.; Dandamudi, Gopi

doi:10.1016/j.cardfail.2019.07.156

Cited by 1 publication

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“…The patient who received a His-bundle pacing had LBBB, and the ejection fraction improved from 25% to 62% and was published as a case report abstract. 6 The LVEF recovered to baseline (from 20% to 45%) in the second patient who had a LBBB, and the LVEF remained unchanged at 30%…”

Section: Cardiac Resynchronization Therapymentioning

confidence: 84%

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Implantable cardioverter defibrillators in patients with orthotopic heart transplant: A multicenter case series

Maskoun

Raad

Cha

et al. 2022

Cardiovasc electrophysiol

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Background Sudden cardiac death (SCD) is common after orthotopic heart transplant (OHT). No clear guidelines for implantable cardioverter defibrillator (ICD) implantation in OHT patients at high risk for SCD currently exist. Objectives To assess the safety, efficacy, and benefit of ICDs and resynchronization therapy post‐OHT. We also provide a systematic review of previous reports. Methods A retrospective multicenter cohort study within the United States. Patients with ICD post‐OHT between 2000 and 2020 were identified. Results We analyzed 16 patients from 4 centers. The mean standard‐deviation (SD) age was 43 (18) years at OHT and 51 (20) years at ICD implantation. The mean (SD) duration from OHT to ICD implantation was 9 (5) years. The mean (SD) left ventricular ejection fraction (LVEF) was 35% (17%). There were 2 (13%) postprocedural complications: 1 hematoma and 1 death. Mean (SD) follow‐up was 24 (23) months. Survival rate was 63% (10/16) at 1 year and 56% (9/16) at 2 years, with 6/7 of those who died having LVEF < 35% at the time of the ICD implantation. Patients were more likely to receive appropriate therapy if their ICD was implanted for secondary (5/8) rather than primary (0/8) prevention (p = .007). Of those who did, 4 patients survived to 30 days post‐ICD therapy. Severe CAV was not associated with the rate of appropriate therapy. Conclusions Beneficial outcomes were observed when ICDs were implanted for secondary prevention only, and in patients with higher baseline LVEF. We also observed benefits with resynchronization therapy.

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Section: Cardiac Resynchronization Therapymentioning

confidence: 84%

“…The patient who received a His‐bundle pacing had LBBB, and the ejection fraction improved from 25% to 62% and was published as a case report abstract 6 …”

Section: Resultsmentioning

confidence: 99%